Imaging trials on cardiovascular disease prevention
| Trial | Imaging node | n | Objective/finding |
| DIAD61 | Myocardial perfusion imaging | 1123 | Small population with lower than anticipated event rates. Myocardial perfusion scanning had no discernible effect on subsequent cardiac events. |
| St Francis56 | Coronary artery calcium score | 1005 | Small population, event curves diverged at 5 years, no effect on slowing progression of coronary calciļ¬cation. |
| PACC55 | Coronary artery calcium score | 1640 | Small population with a high level of zero score scans limiting event numbers. Additionally found to have positive effect on physician prescribing preventive medication and compliance. |
| EISNER48 | Coronary artery calcium score | 2137 | Demonstrated better risk factor control without increasing downstream medical testing in those who underwent calcium scan. |
| FACTOR-6458 | CT coronary angiography | 900 | Small study with no difference detected in outcomes, though close comparison shows failure to deliver treatments depending on scan results. |
DIAD, Detection of Ischemia in Asymptomatic Diabetics; EISNER, Early Identification of Subclinical Atherosclerosis by Noninvasive Imaging Research; FACTOR-64, Screening For Asymptomatic Obstructive Coronary Artery Disease Among High-Risk Diabetic Patients Using CT Angiography, Following Core 64; PACC, Prospective Army Coronary Calcium.