SNPs included in the genetic association study
SNP | Position | Modelled allele | MAF | Beta (SE) |
rs7756935 | 6:46675025 | C | 0.244 | 0.027 (0.004)* |
rs1421368 | 6:46696593 | G | 0.107 | 0.034 (0.006)* |
rs1805017 | 6:46684222 | T | 0.255 | 0.043 (0.004)† |
rs4498351 | 6:46676783 | T | 0.574 | 0.027 (0.004)† |
MAF is from 1000 Genome European populations.
*Per-allele difference in log Lp-PLA2 activity (nmol/min/mL).
†Per-allele difference in log Lp-PLA2 mass (ng/mL).
Lp-PLA2, lipoprotein-associated phospholipase A2; MAF, modelled allele frequency; SNP, single nucleotide polymorphism.