Table 3

Baseline and in-hospital medical therapy

Overallhs-TnI −/BNP −hs-TnI −/BNP +hs-TnI +/BNP −hs-TnI +/BNP +P value
Baseline medical therapy
 ACE inhibitors or ARBs173/397 (43.6)71/208 (34.1)28/59 (47.5)20/40 (50.0)54/90 (60.0)<0.001
 Beta-blockers113/389 (29.1)30/206 (14.6)24/57 (42.1)17/39 (43.6)42/87 (48.3)<0.001
 Calcium-channel blockers63/387 (16.3)12/205 (5.9)13/56 (23.2)13/39 (33.3)25/87 (28.7)<0.001
 Diuretics70/389 (18.0)19/206 (9.2)12/57 (21.1)9/39 (23.1)30/87 (34.5)<0.001
 Insulin25/389 (6.4)5/206 (2.4)3/57 (5.3)4/39 (10.3)13/87 (14.9)0.001
 Lipid lowering86/389 (22.1)22/206 (10.7)16/57 (28.1)10/39 (25.6)38/87 (43.7)<0.001
 Vitamin K antagonists21/389 (5.4)4/206 (1.9)6/57 (10.5)0/39 (0.0)11/87 (12.6)<0.001
 Non-vitamin K antagonists oral anticoagulants14/389 (3.6)5/206 (2.4)4/57 (7.0)1/39 (2.6)4/87 (4.6)0.310
 Aspirin88/389 (22.6)24/206 (11.7)13/57 (22.8)13/39 (33.3)38/87 (43.7)<0.001
 Immunosuppressants15/388 (3.9)6/205 (2.9)2/57 (3.5)2/39 (5.1)5/87 (5.8)0.582
In-hospital medical therapy
 Tocilizumab13/394 (3.3)4/205 (2.0)1/59 (1.7)3/40 (7.5)5/90 (5.6)0.124
 Chloroquine/hydroxychloroquine352/395 (89.1)183/206 (88.8)53/59 (89.8)36/40 (90.0)80/90 (88.9)0.994
 Remdesevir2/395 (0.5)1/206 (0.5)0/59 (0.0)0/40 (0.0)1/90 (1.1)0.729
 Lopinavir/ritonavir213/396 (53.8)107/207 (51.7)31/59 (52.5)23/40 (57.5)52/90 (57.8)0.753
 Darunavir/cobicistat145/395 (36.7)76/206 (36.9)27/59 (45.8)13/40 (32.5)29/90 (32.2)0.366
 Antibiotics369/397 (93.0)196/208 (94.2)54/59 (91.5)35/40 (87.5)84/90 (93.3)0.469
 Immunosuppressive/anti-inflammatory61/395 (15.5)32/206 (15.5)6/59 (10.2)2/40 (5.0)21/90 (3.6)0.031
 Antihypertensive105/394 (26.7)49/205 (23.9)19/59 (32.2)7/40 (17.5)30/90 (33.3)0.139
 ACE inhibitors or ARBs56/395 (14.2)28/206 (13.6)11/59 (18.6)5/40 (12.5)12/90 (13.3)0.760
 Beta-blockers101/395 (25.6)51/206 (24.8)22/59 (37.3)7/40 (17.5)21/90 (23.3)0.115
 Diuretic98/397 (25.0)45/208 (21.6)19/59 (32.2)9/40 (22.5)25/90 (27.8)0.334
 Inotropes/vasopressors57/397 (14.4)21/208 (10.1)9/59 (15.3)7/40 (17.5)20/90 (22.2)0.047
 Heparin313/397 (78.8)165/208 (79.3)46/59 (78.0)31/40 (77.5)71/90 (78.9)0.992
 Non-vitamin K antagonists oral anticoagulants4/394 (1.0)2/205 (1.0)0/59 (0.0)1/40 (2.5)1/90 (1.1)0.684
 Aspirin78/395 (19.8)39/206 (18.9)13/59 (22.0)10/40 (25.0)16/90 (17.8)0.754
  • ARB, angiotensin II receptor blocker; BNP, B-type natriuretic peptide; hs-TnI, high-sensitivity troponin I.