Baseline characteristics of patients with and without recurrent AMI after initial AMI
| All patients | Recurrent AMI | No recurrent AMI | P value | |
| N=3387 | n=84 | n=3303 | ||
| Sociodemographics | ||||
| Age, mean (SD) | 60.7 (11.9) | 66.2 (12.8) | 60.5 (11.8) | <0.001 |
| Age category, years, n (%) | <0.001 | |||
| 18–44 | 307 (9.1) | 5 (6.0) | 302 (9.1) | |
| 45–64 | 1774 (52.4) | 26 (31.0) | 1748 (52.9) | |
| 65–74 | 861 (25.4) | 29 (34.5) | 832 (25.2) | |
| 75–84 | 407 (12.0) | 24 (28.6) | 383 (11.6) | |
| ≥85 | 38 (1.1) | 0 (0.0) | 38 (1.2) | |
| Female, n (%) | 783 (23.1) | 28 (33.3) | 755 (22.9) | 0.025 |
| College degree, n (%) | 462 (13.6) | 9 (10.7) | 453 (13.7) | 0.429 |
| Employed, n (%) | 1420 (41.9) | 20 (23.8) | 1400 (42.4) | <0.001 |
| Medical history and comorbidities, n (%) | ||||
| History of angina | 134 (4.0) | 7 (8.3) | 127 (3.8) | 0.037 |
| History of acute myocardial infarction | 267 (7.9) | 12 (14.3) | 255 (7.7) | 0.027 |
| History of heart failure | 787 (23.2) | 33 (39.3) | 754 (22.8) | <0.001 |
| Dyslipidaemia | 1885 (55.7) | 58 (69.0) | 1827 (55.3) | 0.012 |
| Hypertension | 230 (6.8) | 12 (14.3) | 218 (6.6) | 0.006 |
| Diabetes | 1005 (29.7) | 36 (42.9) | 969 (29.3) | 0.007 |
| Renal dysfunction | 694 (20.5) | 33 (39.3) | 661 (20.0) | <0.001 |
| Clinical characteristics, n (%) | ||||
| Systolic blood pressure at admission <100 mm Hg | 264 (7.8) | 6 (7.1) | 258 (7.8) | 0.822 |
| Heart rate at admission >90 beats/min | 450 (13.3) | 21 (25.0) | 429 (13.0) | 0.001 |
| Ejection fraction <40% | 245 (7.2) | 8 (9.5) | 237 (7.2) | 0.412 |
| ST-segment elevation AMI | 2768 (81.7) | 61 (72.6) | 2707 (82.0) | 0.029 |
| Reperfusion therapies, n (%) | ||||
| PCI | 2363 (69.8) | 33 (39.3) | 2330 (70.5) | <0.001 |
| Thrombolytic therapy | 489 (14.4) | 11 (13.1) | 478 (14.5) | 0.723 |
| In-hospital medications, n (%) | ||||
| Aspirin | 3085 (91.1) | 79 (94.0) | 3006 (91.0) | 0.334 |
| Clopidogrel | 3231 (95.4) | 74 (88.1) | 3157 (95.6) | 0.001 |
| Beta-blocker | 2759 (81.5) | 67 (79.8) | 2692 (81.5) | 0.685 |
| ACEI/ARB | 2486 (73.4) | 54 (64.3) | 2432 (73.6) | 0.056 |
| Statin | 3337 (98.5) | 80 (95.2) | 3257 (98.6) | 0.012 |
| Discharge medications, n (%) | ||||
| Aspirin | 3187 (94.1) | 73 (86.9) | 3114 (94.3) | 0.005 |
| Clopidogrel | 3088 (91.2) | 70 (83.3) | 3018 (91.4) | 0.01 |
| Beta-blocker | 2376 (70.2) | 60 (71.4) | 2316 (70.1) | 0.796 |
| ACEI/ARB | 2136 (63.1) | 52 (61.9) | 2084 (63.1) | 0.824 |
| Statin | 3193 (94.3) | 74 (88.1) | 3119 (94.4) | 0.014 |
| Length of stay, median (IQR) | 11 (8 to 14) | 12 (8 to 14.5) | 11 (8 to 14) | 0.286 |
ACEI, angiotensin-converting enzyme inhibitor; AMI, acute myocardial infarction; ARB, angiotensin receptor blocker; CABG, coronary artery bypass grafting; PCI, percutaneous coronary intervention.