Table 1

Baseline characteristics by treatment allocation

Randomised comparisons
Enhanced self-management
(control)
Supported medical management
(Intervention)
No of participants101101
Age (years), mean (SD)70.4 (11.9)72.8 (11.1)
Sex, female, n (%)31 (31%)26 (26%)
Comorbidities, n (%)
 Hypertension48 (48%)46 (46%)
 Ischaemic heart disease55 (54%)52 (51%)
 Stroke/transient ischaemic attack13 (13%)14 (14%)
 Atrial fibrillation63 (62%)65 (64%)
 Chronic kidney disease14 (14%)16 (16%)
 Diabetes mellitus30 (30%)34 (34%)
 Chronic obstructive lung disease21 (21%)14 (14%)
 Asthma6 (6%)10 (10%)
 Previous venous thromboembolism4 (4%)6 (6%)
Level of competency in use of digital technologies
 Very limited or none, n (%)47 (47%)41 (41%)
 Competent, n (%)46 (46%)51 (50%)
 Expert, n (%)8 (8%)9 (9%)
Left ventricular ejection fraction (%), mean (SD)36.7 (12.4)36.7 (11.6)
Systolic blood pressure (mm Hg), mean (SD)122.6 (18.2)127.5 (21.7)
Diastolic blood pressure (mm Hg), mean (SD)73.7 (10.3)73.7 (10.8)
Heart rate (beats per minute), mean (SD)71.9 (13.1)69.7 (11.7)
Body mass index (kg/m2), mean (SD)28.6 (7)28.3 (5.9)
BNP (pg/mL), median (IQI)187.1 (81.4, 456.7)257.0 (141.2, 386.0)
NT-pro-BNP (pg/mL), median (IQI), n1141.5 (642.0, 1852.0)1570.0 (596.0, 3819.0)
Creatinine (µmol/L), median (IQI), n101.0 (84.0, 133.0)110.0 (87.0, 134.0)
Urea (mmol/L), median (IQI), n8.8 (6.1, 12.0)8.7 (6.6, 11.5)
Potassium (mmol/L), mean (SD)4.5 (0.6)4.5 (0.5)
Haemoglobin (g/dL), median (IQI)13.6 (11.9, 14.3)13.5 (11.5, 14.2)
NYHA class
 Class 132%33%
 Class 224%32%
 Class 337%26%
 Class 48%10%
MAGGIC risk score, mean (SD)22.6 (7.6)22.1 (6.6)
Quality of life and well-being
 MLWHF Overall, mean (SD)36.2 (24.9)35.2 (24.8)
 MLWHF Physical, mean (SD)18.8 (12.3)17.8 (11.8)
 MLWHF Social, mean (SD)9.9 (8.6)10.3 (8.8)
 MLWHF Emotional, mean (SD)7.5 (6.8)7.2 (7)
 EQ5D score, mean (SD)5 (3.4)4.9 (3.9)
  • BNP, brain natriuretic peptide test; MAGGIC, The Meta-analysis Global Group in Chronic Heart Failure; MLWHF, Minnesota Living with Heart Failure questionnaire; n, sample size; NT-pro-BNP, NT-proB-type natriuretic peptide blood test; NYHA, The New York Heart Association Classification for classifying the extent of heart failure; MAGGIC risk score, The MAGGIC risk score is a simple and powerful method of risk stratification for morbidity and mortality in heart failure with preserved ejection fraction; SD, standard deviation.