Table 2

Flow measurements at baseline and following external ventilation in Fontan subjects and controls

CMR flows
(L/min/m2)
BaselinePost-NPVP valuePost-BPVP value
Fontan subjects (n=10)
 SVC0.72 (0.55–0.93)0.75 (0.59–0.90)0.6520.80 (0.74–1.04)0.106
 Fontan1.75 (1.67–2.07)1.99 (1.88–2.47) 0.049 2.36 (1.81–3.02) 0.002
 Sub-IVC0.99 (0.80–1.37)1.16 (0.91–1.48)0.1061.37 (0.88–1.80) 0.027
 HV0.81 (0.62–1.03)0.96 (0.85–1.04)0.1601.06 (0.84–1.42) 0.049
 PoV0.51 (0.37–0.60)0.53 (0.45–0.75)0.1290.55 (0.42–0.60)0.432
 PBF2.48 (2.33–2.99)2.88 (2.51–3.55) 0.037 3.08 (2.70–3.76) 0.002
 CO2.88 (2.28–3.35)2.82 (2.55–3.47)0.4323.28 (2.81–3.72) 0.010
Controls (n=10)
 SVC1.05 (0.97–1.15)1.10 (0.92–1.17)0.7701.01 (0.90–1.15)0.426
 Sup-IVC2.10 (1.97–2.38)2.06 (1.68–2.30)0.1562.19 (1.77–2.47)0.557
 Sub-IVC1.33 (1.17–1.47)1.42 (1.18–1.60)0.7701.39 (1.22–1.64)0.573
 HV0.79 (0.74–1.03)0.64 (0.57–0.96)0.0650.87 (0.72–1.07)0.570
 PoV0.59 (0.51–0.78)0.63 (0.54–0.78)0.5570.51 (0.48–0.64)0.275
 PBF3.37 (3.09–3.81)3.32 (2.86–3.68)0.2322.97 (2.64–3.57)0.084
 CO2.97 (2.76–3.42)3.23 (2.78–3.43)0.8463.13 (2.76–3.45)1.000
  • Data expressed as median (IQR).

  • Bolded figures are statistically significant to p<0.05

  • BPV, biphasic ventilation; CMR, cardiovascular magnetic resonance; CO, cardiac output; HV, hepatic vein; NPV, negative pressure ventilation; PBF, pulmonary blood flow; PoV, portal vein; Sub-IVC, subhepatic inferior vena cava; Sup-IVC, suprahepatic inferior vena cava; SVC, superior vena cava.