Table 3

Effect of external ventilation in Fontan subjects and controls

CMR flows
Δ flow (L/min/m2)
Fontan subjects (n=10)Controls
(n=10)
P value
Effect of NPV
 SVC0.00 (−0.02–0.07)0.04 (−0.31–0.23)0.571
 Fontan/Sup-IVC0.16 (0.11–0.35)−0.21 (0.48–0.05) 0.004
 Sub-IVC0.14 (−0.02–0.26)0.01 (−0.21–0.30)0.472
 HV0.14 (0.01–0.30)−0.21 (−0.38–−0.01) 0.026
 PoV0.07 (−0.01–0.14)0.02 (−0.04–0.10)0.345
 PBF0.20 (0.10–0.53)−0.09 (−0.43–0.09) 0.009
 CO0.17 (−0.11–0.23)0.07 (−0.31–0.23)0.571
Effect of BPV
 SVC0.08 (−0.01–0.19)0.02 (−0.16–0.09)0.089
 Fontan/Sup-IVC0.58 (0.09–0.81)0.00 (−0.50–0.15) 0.009
 Sub-IVC0.22 (0.04–0.58)−0.01 (−0.26–0.30)0.111
 HV0.26 (0.04–0.58)−0.03 (−0.12–0.05) 0.045
 PoV0.05 (−0.05–0.10)−0.04 (−0.12–0.02)0.088
 PBF0.61 (0.20–0.84)−0.27 (−0.55–0.13) 0.001
 CO0.47 (0.21–0.71)0.07 (−0.47–0.33) 0.034
  • Data expressed as median (IQR).

  • BPV, biphasic ventilation; CMR, cardiovascular magnetic resonance; CO, cardiac output; HV, hepatic vein; NPV, negative pressure ventilation; PBF, pulmonary blood flow; PoV, portal vein; Sub-IVC, subhepatic inferior vena cava; Sup-IVC, suprahepatic inferior vena cava; SVC, superior vena cava.