Baseline characteristics (prior to pregnancy) for patients with and without aortic dilatation
| Ascending aortic dilatation* N=81 | No aortic dilatation† N=59 | P value | |
| Age (median (IQR)) | 31.1 (28.1–34.3) | 28.3 (25.7–32.3) | 0.01 |
| Nulliparity | 42/81 (52%) | 31/59 (53%) | 0.59 |
| Hypertension | 9/81 (10%) | 11/59 (19%) | 0.18 |
| Smoking (current-former) | 1-10/62 | 3-7/54 | 0.51 |
| BMI (median (IQR)) | 23.7 (21.3–27.8) | 24.4 (20.5–27.9) | 0.98 |
| Aortic diameter | 42 (38–46.5) | / | / |
| Prior aortic dissection | 3/81 (4%) | 5/59 (8%) | 0.36 |
| A | 3 | 5 | |
| B | / | / | |
| BAV | 27/81 (33%) | 18/59 (31%) | 0.72 |
| Valvular intervention | |||
| Aortic | 8 (6M, 2R) | 3 (1B, 2?) | |
| Mitral | 5 (1M, 1B, 3?) | / | |
| Treatment | |||
| BB | 27/49 (55%) | 14/27 (52%) | 0.81 |
| ACE-I | 3/55 (5,5%) | 0/30 | 0.55 |
| ARB | 0/47 | 1/25 (4%) | 0.35 |
| Diuretics | 1/55 | 0/30 | 1.0 |
| VKA | 9/23 (39%) | 0/9 | 0.035 |
Categorical variables are presented as count divided by the total number of valid/available data and percentages between brackets.
*Presence of aortic dilatation at moment of inclusion.
†Data on aortic dilatation were missing in 49 cases.
ACE-I, ACE inhibitor; ARB, angiotensin receptor blocking agent; BAV, bicuspid aortic valve; B, bioprosthesis; BB, beta-blocking agent; M, mechanical valve; R, valve repair; VKA, vitamin K antagonist.;