Standard and advanced echocardiographic characteristics of patients with MVP with and without VAs
| Overall population N=610 | MVP without VA N=543 | MVP with VA N=67 | P value | |
| LVEDd, mm | 54 (±6) | 54 (±6) | 55 (±7) | 0.183 |
| LVESd, mm | 33 (±7) | 33 (±6) | 34 (±7) | 0.089 |
| MV annulus, mm | 33 (±6) | 33 (±6) | 37 (±5) | <0.001 |
| LVEDV, mL | 135 (±42) | 135 (±42) | 138 (±41) | 0.500 |
| LVESV, mL | 46 (±17) | 46 (±17) | 50 (±18) | 0.087 |
| LVEF, % | 66 (±6) | 66 (±6) | 65 (±6) | 0.097 |
| LAd, mm | 45 (±7) | 45 (±7) | 43 (±8) | 0.221 |
| LAVI mL/m2 | 50 (IQR 38–62) | 50 (IQR 39–62) | 49 (IQR 37–67) | 0.812 |
| GLS, %* | 21.9 (±3.5) | 22.0 (±3.6) | 20.9 (±3.1) | 0.032 |
| PST, %* | 1.41 (IQR 0.47–3.24) | 1.35 (IQR 0.47–3.12) | 2.18 (IQR 0.60–4.16) | 0.057 |
| PSI, %* | 2.88 (IQR 1.59–4.71) | 2.76 (IQR 1.53–4.53) | 3.71 (IQR 2.03–6.10) | 0.014 |
| MD, ms* | 39 (±13) | 38 (±14) | 45 (±12) | 0.003 |
| MAD, n (%) | 133 (22%) | 107 (20%) | 26 (39%) | <0.001 |
| MAD value, mm | 7.0 (IQR 6.0–9.0) | 7.0 (IQR 6.0–9.0) | 8.0 (IQR 7.0–10.0) | 0.035 |
| Curling LV†, n (%) | 255 (42%) | 213 (39%) | 42 (63%) | <0.001 |
| MV flail, n (%) | 173 (28%) | 158 (29%) | 15 (22%) | 0.250 |
*Only available in a subset of patients.
†defined as outward movement of the MV annulus during systole.
d, diameter; ED, end-diastolic; EF, ejection fraction; ES, end-systolic; GLS, global longitudinal strain; LA, left atrium; LAVI, left atrial volume index; LV, left ventricle; MAD, mitral annular disjunction; MD, mechanical dispersion; MR, mitral regurgitation; MV, mitral valve; PSI, postsystolic index; PST, prestretch index; V, volume; VA, ventricular arrhythmia.