Baseline demographic and clinical characteristics
| Disease status: CRP requirement (mg/dL): n: | Idiopathic | PPS | Total | |||
| Active*
>1 12 | Active† ≤1 3 | CS-dep‡ N/A 6 | Active§ >1 1 | CS-dep¶ N/A 3 | All*†‡§¶ N/A 25 | |
| Mean (median, range, SD) age, years | 39.6 (42.5, 26–52,10.2) | 42.7 (42.0, 28–58,15.0) | 51.3 (50.5, 40–62,7.8) | 34.0 | 42.0 (40.0, 36–50, 7.2) | 42.8 (44.0, 26–62, 10.5) |
| Female sex, n (%) | 9 (75.0) | 3 (100.0) | 2 (33.3) | 0 | 1 (33.3) | 15 (60.0) |
| Race, n (%) | ||||||
| White | 10 (83.3) | 2 (66.7) | 6 (100.0) | 1 (100.0) | 3 (100.0) | 22 (88.0) |
| Black/African-American | 2 (16.7) | 1 (33.3) | 0 | 0 | 0 | 3 (12.0) |
| Mean (median, range, SD) BMI, kg/m2 | 30.2 (29.4, 23.4–39.0, 5.4) | 40.0 (38.5, 28.7–52.7, 12.1) | 31.1 (33.1, 23.7–34.3, 4.1) | 29.3 | 24.7 (25.0, 22.5–26.6, 2.1) | 30.9 (29.3, 22.5–52.7, 6.7) |
| Mean (median, range, SD) pain rating, NRS** | 4.6 (5.0, 2–8, 1.7) | 4.7 (4.0, 2–8, 3.1) | 1.2 (1.0, 0–2, 0.8) | 4.0 | 2.0 (1.0, 0–5, 2.7) | 3.4 (3.0, 0–8, 2.3) |
| Mean (median, range, SD) baseline CRP, mg/dL | 4.9 (2.1, 0.8–19.8, 5.8) | 0.5 (0.3, 0.1–1.0, 0.4) | 0.2 (0.2, 0.1–0.4, 0.1) | 1.1 | 0.1 (0.1, 0.1–0.2, 0.05) | 2.5 (0.92, 0.1–19.8, 4.6) |
| Pericarditis medications, n (%) | ||||||
| Aspirin | 0 | 0 | 2 (33.3) | 0 | 0 | 2 (8.0) |
| NSAIDs | 6 (50.0) | 1 (33.3) | 4 (66.7) | 0 | 1 (33.3) | 12 (48.0) |
| Colchicine | 8 (66.7) | 3 (100.0) | 6 (100.0) | 1 (100.0) | 2 (66.7) | 20 (80.0) |
| Corticosteroids | 4 (33.3) | 2 (66.7) | 6 (100.0) | 0 | 3 (100.0) | 15 (60.0) |
| Pericarditis medication categories, n (%) | ||||||
| 0 | 3 (25.0) | 0 | 0 | 0 | 0 | 3 (12.0) |
| 1 | 2 (16.7) | 0 | 0 | 1 (100.0) | 0 | 3 (12.0) |
| 2 | 5 (41.7) | 3 (100.0) | 0 | 0 | 3 (100.0) | 11 (44.0) |
| ≥3 | 2 (16.7) | 0 | 6 (100.0) | 0 | 0 | 8 (32.0) |
| Number of previous pericarditis recurrences | ||||||
| Mean | 1.8 | 2.0 | 3.3 | 8.0 | 3.3 | 2.6 |
*Part 1.
†Part 2.
‡Part 3.
§Part 4.
¶Part 5.
**11-point numeric scale, ranging from zero (0, no pain) to 10 (10, pain as bad as possible).
BMI, body mass index; CRP, C reactive protein; CS-dep, corticosteroid dependent; NRS, numeric rating scale; NSAIDs, nonsteroidal anti-inflammatory drugs; PPS, postpericardiotomy syndrome.;