Table 1

Summary of included studies and baseline characteristics

Study	Country	Monocentric/multicentric	NIH	Patients (n)	Age (mean, years)	Sex, male (%)	HTN (%)	DM (%)	SM (%)	DL (%)	CAD (%)
Claeys et al 16	Belgium	Multicentric	Good	949*	63.0	75	47	17	n/a	n/a	12
De Rosa et al 5	Italy	Multicentric	Good	465	65.9	77	n/a	n/a	n/a	n/a	n/a
Gramegna et al 8	Italy	Monocentric	Good	47	65.6	79	53	23	26	49	21
Reinstadler et al 1	Austria	Multicentric	Good	163	64.3	73	63	20	44	81	21
Romaguera et al 17	Spain	Multicentric	Good	919	62.8	80	n/a	n/a	n/a	n/a	n/a
Scholz et al 10	Germany	Multicentric	Good	1716	63.8	72	59	20	40	29	n/a
Trabattoni et al 15	Italy	Monocentric	Fair	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wu et al 19	England	Multicentric	Good	17 246	65.7	72	39	19	30	24	n/a
Xiang et al 7	China	Multicentric	Good	28 189	62.7	67	n/a	n/a	n/a	n/a	n/a
Zhang et al 18	China	Monocentric	Good	395	n/a	n/a	n/a	n/a	n/a	n/a	n/a

NIH: study quality as per the National Institutes of Health (NIH) Quality Assessment Tool.
*Claeys et al:16 baseline characteristics of 595 patients were assessed.
CAD, coronary artery disease (known); DL, dyslipidaemia; DM, diabetes mellitus; HTN, hypertension (arterial); n/a, not available (data); SM, smoker.