Echocardiography parameters
| Echocardiographic measurement | Baseline |
| Left ventricular end diastolic volume, median mL (IQR) | 76 (57–99) |
| Left ventricular end systolic volume, median mL (IQR) | 30 (22–42) |
| Stroke volume, median mL (IQR) | 55 (45–64) |
| Left ventricular ejection fraction, median % (IQR) | 59 (52–64) |
| Global longitudinal strain, median % (IQR) | −14 (−12 to −15) |
| Lateral s’, median cm/s (IQR) | 6.7 (5.6–7.9) |
| Septal s’, median cm/s (IQR) | 6.1 (5.1–7.2) |
| Average e’, median cm/s (IQR) | 9.3 (8.1–10.9) |
| Mitral E velocity, median cm/s (IQR) | 89.7 (77.1–102.8) |
| Mitral deceleration time, median ms (IQR) | 212 (188–234) |
| Average E/e’, median (IQR) | 9.4 (7.8–11.7) |
| Isovolumic relaxation time, median ms (IQR) | 97 (89–108) |
| Pulmonary vein ratio, mean (SD) | 0.7 (0.1) |
| Pulmonary vein deceleration time, median (IQR) | 242 (223–258) |
| Left atrial volume indexed to BSA, median mL/m2 (IQR) | 38 (32–49) |
| Left atrial ejection fraction, median % (IQR) | 23 (15–33) |
| TAPSE mm, median (IQR) | 18.7 (17.1–21.8) |
BSA, body surface area; TAPSE, tricuspid annular plane systolic excursion.