Unadjusted change from baseline health status scores after AMI, stratified by diabetes status
| Health status outcomes | Without diabetes (n=2008, 57.4% of 3501 participants) (a) | P value* changes in (b) vs (a) | Newly diagnosed diabetes (n=508, 14.5% of 3501 participants) (b) | P value† changes in (b) vs (c) | Established diabetes (n=985, 28.1% of 3501 participants) Mean (SD) (c) | ||||||
| Baseline mean (SD) | Follow-Up mean (SD) | Change from baseline mean (95% CI) | Baseline mean (SD) | Follow-Up mean (SD) | Change from baseline mean (95% CI) | Baseline mean (SD) | Follow-up mean (SD) | Change from baseline mean (95% CI) | |||
| 1-month follow-up | |||||||||||
| SAQ-Angina Frequency | 85.84 (18.94) | 89.51 (17.27) | 4.03 (2.89 to 5.18) | 0.685 | 85.50 (18.12) | 89.36 (17.89) | 3.54 (1.39 to 5.69) | 0.005 | 79.33 (23.73) | 87.39 (18.53) | 8.56 (6.73 to 10.39) |
| SAQ-Physical Limitations | 84.56 (22.93) | 89.90 (19.09) | 7.08 (5.82 to 8.34) | 0.294 | 82.51 (24.96) | 90.89 (18.54) | 8.67 (5.98 to 11.36) | 0.001 | 73.77 (28.72) | 88.91 (20.94) | 16.05 (13.95 to 18.16) |
| SAQ-Quality of Life | 57.48 (22.84) | 67.94 (24.57) | 11.62 (10.20 to 13.04) | 0.729 | 59.96 (25.29) | 71.27 (24.41) | 11.10 (8.42 to 13.78) | 0.118 | 52.94 (25.25) | 66.39 (26.40) | 13.81 (11.75 to 15.88) |
| SF-12 Mental Functioning | 46.36 (12.37) | 49.61 (10.85) | 2.77 (2.13 to 3.42) | 0.001 | 45.84 (12.14) | 51.54 (9.50) | 5.65 (4.43 to 6.87) | 0.370 | 43.21 (12.81) | 48.61 (11.21) | 4.95 (4.04 to 5.87) |
| SF-12 Physical Functioning | 45.84 (11.65) | 43.51 (11.28) | −1.98 (-2.61 to -1.35) | 0.616 | 44.24 (11.82) | 42.06 (11.78) | −2.31 (-3.47 to -1.16) | 0.148 | 39.71 (12.06) | 38.10 (11.75) | −1.28 (−2.11 to -0.45) |
| EQ-5D-VAS | 66.34 (20.62) | 71.75 (20.09) | 16.82 (15.99 to 17.66) | 0.888 | 67.06 (21.11) | 72.04 (19.90) | 16.94 (15.48 to 18.41) | 0.078 | 58.49 (22.27) | 67.37 (22.40) | 18.64 (17.49 to 19.79) |
| 12-month follow-up | |||||||||||
| SAQ-Angina Frequency | 85.84 (18.94) | 92.06 (16.03) | 6.66 (5.51 to 7.82) | 0.623 | 85.50 (18.12) | 92.56 (14.37) | 7.26 (5.22 to 9.30) | 0.111 | 79.33 (23.73) | 89.21 (19.12) | 9.60 (7.56 to 11.63) |
| SAQ-Physical Limitations | 84.56 (22.93) | 91.87 (17.98) | 8.29 (6.97 to 9.61) | 0.127 | 82.51 (24.96) | 93.31 (16.03) | 10.59 (7.94 to 13.23) | 0.005 | 73.77 (28.72) | 89.79 (21.62) | 15.62 (13.31 to 17.93) |
| SAQ-Quality of Life | 57.48 (22.84) | 72.23 (22.51) | 15.35 (13.90 to 16.79) | 0.801 | 59.96 (25.29) | 75.74 (22.01) | 15.76 (12.91 to 18.61) | 0.367 | 52.94 (25.25) | 70.32 (24.88) | 17.43 (15.18 to 19.69) |
| SF-12 Mental Functioning | 46.36 (12.37) | 50.61 (10.80) | 3.88 (3.19 to 4.57) | 0.096 | 45.84 (12.14) | 51.27 (9.70) | 5.09 (3.79 to 6.40) | 0.979 | 43.21 (12.81) | 48.81 (11.79) | 5.12 (4.03 to 6.20) |
| SF-12 Physical Functioning | 45.84 (11.65) | 46.14 (11.55) | 0.66 (0.00 to 1.32) | 0.581 | 44.24 (11.82) | 45.03 (12.21) | 0.23 (-1.12 to 1.58) | 0.532 | 39.71 (12.06) | 40.61 (12.83) | 0.76 (−0.19 to 1.70) |
| EQ-5D-VAS | 66.34 (20.62) | 73.61 (20.22) | 8.09 (6.80 to 9.37) | 0.965 | 67.06 (21.11) | 75.73 (18.34) | 8.03 (5.65 to 10.40) | 0.202 | 58.49 (22.27) | 68.55 (22.87) | 10.05 (8.03 to 12.06) |
P-value numbers in bold denote statistical significance at the p<0.05 level.
*Unadjusted p values were testing for differences in mean changes of health status scores between patients with newly diagnosed and without diabetes.
†Unadjusted p values were testing for differences in mean changes of health status scores between patients with newly diagnosed and established diabetes.
EQ-5D-VAS, Euro-Quality of Visual Analogue Scale; SAQ, Seattle Angina Questionnaire; SF-12, 12 Item Short Form Survey.