Table 2

Event rates (per 100 person-years) within 2-year follow-up by treatment at baseline

Treatment at baselineOutcome
All-cause mortalityNon-haemorrhagic stroke/SEMajor bleeding
EventsRate (95% CI)EventsRate (95% CI)EventsRate (95% CI)
FXaI5363.7 (3.4 to 4.0)1120.8 (0.6 to 0.9)1521.0 (0.9 to 1.2)
DTI1303.3 (2.8 to 3.9)340.9 (0.6 to 1.2)290.7 (0.5 to 1.1)
Any NOAC6663.6 (3.3 to 3.9)1460.8 (0.7 to 0.9)1811.0 (0.9 to 1.1)
VKA7734.8 (4.5 to 5.2)1531.0 (0.8 to 1.1)2231.4 (1.2 to 1.6)
Any OAC14394.1 (3.9 to 4.4)2990.9 (0.8 to 1.0)4041.2 (1.1 to 1.3)
No OAC7375.6 (5.2 to 6.0)1681.3 (1.1 to 1.5)1020.8 (0.6 to 1.0)
  • DTI, direct thrombin inhibitor; FXaI, factor Xa inhibitor; NOAC, non-vitamin K antagonist oral anticoagulant; OAC, oral anticoagulant; SE, systemic embolism; VKA, vitamin K antagonist.