Clinical characteristics and medications on arrival
| Prasugrel | Ticagrelor | P value | |
| Patients, n | 2073 | 35 917 | |
| Diagnosis | |||
| STEMI | 1508 (72.8) | 16 619 (46.3) | <0.001 |
| NSTEMI | 563 (27.2) | 19 296 (53.7) | |
| Clinical characteristics on arrival | |||
| CPR outside hospital | 66 (3.2) | 759 (2.1) | 0.001 |
| Thrombolysis before admission | 128 (6.2) | 189 (0.5) | <0.001 |
| Atrial fibrillation on arrival | 42 (2.0) | 797 (2.2) | 0.570 |
| Heart rate, pulse/min, mean±SD | 76 (19) | 78 (19) | 0.003 |
| Systolic blood pressure, mm Hg, mean±SD | 144 (28) | 150 (29) | <0.001 |
| Killip class II–IV | 105 (5.2) | 1815 (5.1) | 0.924 |
| Laboratory data index | |||
| Estimated GFR, mL/min/1.73 m2 | 84 (24) | 81 (24) | <0.001 |
| ≤60 mL/min/1.73 m2 | 265 (13.2) | 5577 (16.3) | <0.001 |
| Anaemia | 418 (20.8) | 6753 (20.0) | 0.369 |
| Crusade bleeding score, median (25th–75th percentile) | 20 (14–27) | 21 (16–29) | <0.001 |
| Medication on arrival | |||
| Oral anticoagulant | 9 (0.4) | 127 (0.4) | 0.246 |
| Aspirin | 620 (30.1) | 9925 (28.0) | 0.034 |
| P2Y12 receptor inhibitor | |||
| Clopidogrel | 164 (8.0) | 767 (2.2) | <0.001 |
| Ticagrelor | 31 (1.5) | 503 (1.4) | |
| Prasugrel | 5 (0.2) | 2 (0.0) | |
| Beta blocker | 609 (29.7) | 9600 (27.1) | 0.010 |
| ACE-I/ARB | 734 (35.8) | 11 677 (33.0) | 0.008 |
| Antidiabetic medication | |||
| Oral | 166 (8.1) | 2736 (7.7) | 0.010 |
| Insulin | 209 (10.1) | 2955 (8.3) | |
| Statin | 616 (29.9) | 8858 (25.0) | <0.001 |
| Diuretic | 264 (12.9) | 4795 (13.5) | 0.400 |
Results are presented as numbers and percentages unless otherwise indicated.
ACE-I, ACE inhibitor; ARB, angiotensin receptor blocker; CPR, cardiopulmonary resuscitation; GFR, glomerular filtration rate; NSTEMI, non-ST segment elevation myocardial infarction; STEMI, ST segment elevation myocardial infarction.