Table 3

In-hospital management and medications at discharge

PrasugrelTicagrelorP value
Patients, n207335 917
Percutaneous coronary intervention
Access site—radial artery1359 (65.7)28 980 (81.0)<0.001
Multivessel disease1075 (52.1)17 669 (49.5)0.022
PCI with stent1917 (92.7)3329 (93.1)0.491
Medication before/during PCI*
Aspirin2027 (97.7)35 255 (98.2)0.165
P2Y12 receptor inhibitor, before PCI1871 (90.3)31 272 (87.1)<0.001
 Clopidogrel1129 (54.5)3594 (10.0)<0.001
 Ticagrelor159 (7.7)27 736 (77.2)
 Prasugrel632 (30.5)339 (0.9)
P2Y12 receptor inhibitor, during PCI746 (36.0)5457 (15.2)<0.001
 Clopidogrel49 (2.4)333 (0.9)<0.001
 Ticagrelor22 (1.1)5255 (14.6)
 Prasugrel696 (33.6)101 (0.3)
P2Y12 receptor inhibitors, before/during PCI2045 (98.6)35 000 (97.4)<0.001
 Clopidogrel360 (27.0)1957 (5.4)<0.001
 Ticagrelor176 (8.5)32 610 (90.8)
 Prasugrel1309 (63.1)433 (1.2)
Unfractionated heparin1786 (86.2)33 409 (93.0)<0.001
Glycoprotein IIb/IIIa receptor inhibitor154 (7.4)2511 (7.0)0.448
During the index hospitalisation
CPAP51 (2.5)897 (2.5)0.914
New-onset AF55 (2.7)874 (2.4)0.531
Intravenous diuretic310 (15.0)4127 (11.5)<0.001
Inotropic drug105 (5.1)917 (2.6)<0.001
LMWH/fondaparinux744 (35.9)16 102 (47.1)<0.001
Medication at discharge
Aspirin2073 (100)35 197 (100)NA
Beta blocker1908 (92.0)32 608 (90.8)0.056
ACE-I/ARB1844 (89.0)30 988 (86.3)0.001
Statin2024 (97.6)35 015 (97.5)0.687
Antidiabetic medication
 Oral182 (8.8)3047 (8.5)0.002
 Insulin225 (10.9)3123 (8.7)
Diuretic366 (17.7)5765 (16.1)0.054
  • Results are presented as numbers and percentages unless otherwise indicated.

  • *Were administrated the last 24 hours before or during PCI.

  • ACE-I, ACE inhibitor; AF, atrial fibrillation; ARB, angiotensin receptor blocker; CPAP, continuous positive airway pressure; LMWH, low molecular weight heparin; NA, not applicable; PCI, percutaneous coronary intervention.