Determinants of successful weight loss in the intervention group; candidate variables stratified by successful weight reduction (≥5% of baseline weight)
| Univariable analysis | Multivariable model* | |||||
| Successful patients (%) (n=90) | Unsuccessful patients (%) (n=190) | OR (95% CI) | P value | OR (95% CI) | P value | |
| Demographics | ||||||
| Age (≥65 years) | 39 (43.3) | 36 (19.0) | 3.27 (1.88 to 5.67) | <0.001 | 2.94 (1.57 to 5.48) | <0.001 |
| Sex (female) | 26 (28.9) | 39 (20.5) | 1.57 (0.88 to 2.79) | 0.12 | ||
| Level of education (lower)† | 62 (68.9) | 113 (59.5) | 1.51 (0.87 to 2.57) | 0.13 | 1.91 (1.05 to 3.50) | 0.04 |
| Having a partner | 77 (85.6) | 157 (82.6) | 1.24 (0.63 to 2.58) | 0.54 | ||
| Baseline lifestyle-related risk factors | ||||||
| Non-smoking status‡ | 69 (76.7) | 89 (46.8) | 3.73 (2.12 to 6.56) | <0.001 | 2.92 (1.56 to 5.46) | <0.001 |
| BMI, kg/m2 | 32.0±3.4 | 31.5±3.6 | 1.04 (0.97 to 1.12) | 0.23 | ||
| Inadequate physical activity§ | 33 (36.7) | 75 (39.5) | 0.89 (0.53 to 1.49) | 0.65 | ||
| Overweight as only lifestyle-related risk factor | 27 (30.0) | 38 (20.0) | 1.71 (0.96 to 3.04) | 0.07 | ||
| Participation in lifestyle programmes | ||||||
| Smoking cessation programme | 4 (4.4) | 26 (13.7) | 0.29 (0.08 to 0.78) | 0.03 | ||
| Physical activity programme | 52 (57.8) | 107 (56.3) | 1.06 (0.64 to 1.77) | 0.82 | ||
| Weight loss programme (WW) | 76 (84.4) | 106 (55.8) | 4.30 (2.33 to 8.42) | <0.001 | 3.33 (1.60 to 6.99) | 0.002 |
| Partner participating in WW | 42 (65.6) | 39 (42.9) | 2.55 (1.32 to 4.99) | <0.01 | ||
| Motivation variables | ||||||
| Motivated for WW | 77 (92.8) | 139 (78.1) | 3.60 (1.56 to 9.81) | <0.01 | ||
| Motivated to start WW directly after the baseline visit | 77 (92.8) | 131 (71.2) | 5.19 (2.29 to 14.00) | <0.001 | 2.31 (0.88 to 6.02) | 0.09 |
| Referred to WW in first outpatient clinic visit | 69 (89.6) | 109 (83.2) | 1.74 (0.76 to 4.37) | 0.21 | ||
Values presented as mean±SD or counts (%).
*Variables selected with backward elimination (p<0.157) in 20 imputed datasets and estimates pooled using Rubins’ rule.
†Lower education: all except universities of applied sciences and research universities.
‡Never smoking or quit >6 months before hospitalisation.
§Self-reported based on WHO recommendations.
BMI, body mass index.