Changes in the laboratory values 6 months after initiation of sacubitril/valsartan treatment, n=18
| Laboratory values | Mean±SD or median (IQR) Baseline | Mean±SD or median (IQR) 6 months | P value |
| Hb (mmol/L) | 8.7±0.9 | 8.9±0.9 | 0.083 |
| Ht (L/L) | 0.42±0.04 | 0.43±0.04 | 0.004* |
| MCV (fL) | 89±5 | 91±3 | 0.006* |
| MCH (fmol) | 1.84±0.12 | 1.86±0.07 | 0.251 |
| RDW (%) | 13.0±1.2 | 12.9±1.1 | 0.252 |
| Sodium (mmol/L) | 140±2 | 141±2 | 0.182 |
| Potassium (mmol/L) | 4.3±0.4 | 4.5±0.3 | 0.011* |
| Creatinine (μmol/L) | 86±18 | 89±14 | 0.095 |
| eGFR (mL/min/1.73 m2) | 85±20 | 80±21 | 0.087 |
| BUN (mmol/L) | 6.5 (5.5–6.8) | 6.3 (4.9–7.5) | 0.649 |
| ASAT (U/L) | 31±13 | 29±13 | 0.162 |
| ALAT (U/L) | 30±11 | 26±12 | 0.013* |
| Gamma GT (U/L) | 39 (26–82) | 43 (27–62) | 0.767 |
| Total bilirubin (μmol/L) | 11.5 (7.8–18.3) | 10 (8.0–17.0) | 0.550 |
| CK (U/L) | 93±40 | 105±58 | 0.328 |
| Troponin T (ng/L) | 11.0 (5.3–16.8) | 7.5 (6.0–11.3) | 0.109 |
| NT-pro-BNP (ng/L) | 950 (364–1235) | 358 (233–639) | <0.001* |
*Statistically significant.
ALAT, alanine transaminase; ASAT, aspartase aminotransferase; BUN, blood urea nitrogen; Gamma GT, gamma glutamyltransferase; Hb, haemoglobin; Ht, haematocrit; MCH, mean corpuscular haemoglobin; MCV, mean corpuscular volume; NT-pro-BNP, N-terminal pro–B-type natriuretic peptide; RDW, red blood cell distribution width.;