Table 3

MRI findings

Patients with
COVID-19 (n=52)
Comorbidity-matched volunteers (n=26)Healthy
volunteers (n=10)
P value*P value†
LVEDVI, mean±SD (95% CI), (mL/m2)73.1±18.1
(68.1 to 78.1)
78.5±20
(67 to 81.0)
79.2±18.3
(72.6 to 43.7)
0.990.17
LVESVI, mean±SD (95% CI), (mL/m2)32.1±16.1
(27.6 to 36.4)
31.7±16.2
(26.0 to 37.9)
25.8±7.9
(22.5 to 30.1)
0.920.04
Stroke volume index, mean±SD (95% CI), (mL/m2)41.3±10.8
(38.3 to 44.1)
44.9±8.7
(40.0 to 50.4)
52.1±10.6
(46.5 to 56.3)
0.120.001
LV ejection fraction, mean±SD (95% CI), (%)57.4±11.1
(54.0 to 60.1)
61.6±9.9
(56.1 to 65.2)
66.3±5.3
(62.4 to 69.8)
0.150.02
LV mass index, mean±SD (95% CI), (g/m2)53.5±11.0
(50.4 to 56.6)
56.6±12.2
(51.8 to 60.2)
55.7±15.2
(50.6 to 61.4)
0.210.81
RVEDVI, mean±SD (95% CI), (mL/m2)79.3±16.2
(74.8 to 83.8)
75.4±12.3
(70.4 to 80.40
74.5±9.8
(68.6 to 80.4)
0.270.06
RVESVI, mean±SD (95% CI), (mL/m2)39.9±15.3
(34.7 to 43.3)
30.1±7.8
(28.2 to 33.5)
29.3±5.4
(26.1 to 32.6)
0.0060.02
RV stroke volume Index, mean±SD (95% CI), (mL/m2)39.8±9.7
(37.2 to 42.6)
45.1±9.8
(45.2 to 55.7)
47.5±9.3
(42.1 to 52.9)
0.020.01
RV ejection fraction, mean±SD (95% CI), (%)51.7±9.1
(53.9 to 60.1)
59.3±4.9
(51.0 to 66.5)
60.5±4.9
(57.1 to 63.2)
0.0005<0.0001
Main pulmonary artery, mean±SD (mm)20.7±3.122.8±6.618.5±4.00.090.05
Late gadolinium enhancement pattern, n (%)18 (35)9 (35)0
Ischaemic9 (17)5 (19)
Non-ischaemic9 (17)4 (15)
Native T1-septum, mean±SD (95% CI), (ms)1225±46‡
(1205 to 1240)
1227±51§
(1208 to 1246)
1197±30
(1178 to 1216)
0.990.04
Global T1- midventricular, mean±SD (95% CI), (ms)1210±38‡
(1193 to 1226)
1208±33§
(1191 to 1228)
1184±24
(1168 to 1200)
0.880.04
Extracellular volume, mean±SD (95% CI), (%)31±4
(29.6 to 32.1)
29±5
(27.0 to 31.2)
24±3
(22.4 to 26.4)
0.350.0003
T2 septum, mean±SD (95% CI), (ms)37.3±4.6
(35.9 to 38.6)
38.5±5.9
(36.1 to 40.1)
38.7±3
(37.4 to 40.1)
0.350.18
Manganese influx constant, mean±SD (95% CI),
(Ki/mL/100 g/min)
6.9±0.9‡
(6.5 to 7.3)
7.3±1.3§
(6.7 to 7.9)
7.9±1.2
(7.4 to 8.5)
0.450.01
  • Bold values are statistically significant (<0.05).

  • *Patients with COVID-19 versus comorbidity-matched volunteers.

  • †Patients with COVID-19 versus healthy volunteers.

  • ‡n=23.

  • §n=20.

  • LV, left ventricular; LVEDVI, indexed left ventricular end-diastolic volume; LVESVI, indexed left ventricular end-systolic volume; RV, right ventricular; RVEDVI, indexed right ventricular end-diastolic volume; RVESVI, indexed right ventricular end-systolic volume.