Outcome | Conventional treatment (n=83) | Early PMC (n=84) | HR* (95% CI) | P value |
Composite primary endpoint, n (%) | 9 (10.8) | 7 (8.3) | 0.77 (0.29 to 2.07) | 0.61 |
PMC-related complications | 1 (1.2) | 0 (0) | ||
Procedural mortality | 0 | 0 | ||
Urgent mitral valve surgery | 1 | 0 | ||
Cardiovascular mortality | 0 (0) | 3 (3.6) | ||
Non-fatal cerebral infarction | 6 (7.2) | 3 (3.6) | ||
Systemic thromboembolic event | 2 (2.4) | 1 (1.2) | ||
Secondary endpoints, n (%) | ||||
Death from any cause | 3 (3.6) | 4 (4.8) | 1.30 (0.29 to 5.77) | 0.73 |
Mitral valve replacement | 17 (20.5) | 10 (11.9) | 0.59 (0.27 to 1.29) | 0.19 |
*HRs were calculated with the use of stratified Cox proportional hazards models with Firth correction.
PMC, percutaneous mitral commissurotomy.