Nine-predictor Fine-Gray subdistribution hazard model estimates depicting adjusted effects on cumulative incidence function of major bleeding
Parameter | Bootstrap results | |||||||
Parameter estimate | χ2 | P value | sHR | Lower 95% CI for sHR | Upper 95% CI for sHR | Mean estimate | Mean sHR | |
Anaemia | 0.34 | 17.4 | <0.0001 | 1.41 | 1.20 | 1.65 | 0.34 | 1.40 |
Concurrent antiplatelet therapy | 0.45 | 11.9 | 0.0006 | 1.57 | 1.21 | 2.02 | 0.44 | 1.56 |
eGFR (per 1 unit) | −0.01 | 10.5 | 0.0012 | 0.99 | 0.99 | 1.00 | −0.01 | 0.99 |
Fall risk | 0.24 | 8.4 | 0.0037 | 1.27 | 1.08 | 1.49 | 0.24 | 1.27 |
Gender (male vs female) | 0.43 | 25.6 | <0.0001 | 1.54 | 1.30 | 1.82 | 0.44 | 1.55 |
Hypertension | 0.52 | 8.5 | 0.0036 | 1.68 | 1.18 | 2.38 | 0.54 | 1.74 |
Log cholesterol (per 1 unit) | −0.37 | 4.2 | 0.0398 | 0.69 | 0.49 | 0.98 | −0.37 | 0.71 |
Prior major bleeding | 0.31 | 15.7 | <0.0001 | 1.37 | 1.17 | 1.59 | 0.31 | 1.37 |
Thrombocytopaenia (moderate/severe vs normal/mild) | 0.57 | 5.3 | 0.0212 | 1.77 | 1.09 | 2.87 | 0.54 | 1.76 |
eGFR, estimated glomerular filtration rate; sHR, subdistribution hazard ratio.