Association of NT-proBNP and BNP with hospital admission at 1 year in people with a new diagnosis of heart failure
| n/N | Unadjusted (N=27 258) | Partially adjusted* (N=27 258) | Fully adjusted† (N=24 434) | |
| OR (95% CI) | OR (95% CI) | OR (95% CI) | ||
| NT-proBNP group (pg/mL) | ||||
| <400 | 4969/9148 | 1.047 (0.990 to 1.108) | 1.029 (0.972 to 1.089) | 1.032 (0.971 to 1.097) |
| 400–1999.9 (Reference) | 5709/10 738 | 1.000 | 1.000 | 1.000 |
| 2000+ | 4199/7372 | 1.166 (1.098 to 1.237) | 1.169 (1.101 to 1.241) | 1.203 (1.128 to 1.283) |
| NT-proBNP (per 100 pg/mL) | 14 877/27 258 | 1.0013 (1.0006 to 1.0019) | 1.0014 (1.0008 to 1.0021) | 1.0018 (1.0010 to 1.0025) |
| n/N | Unadjusted (N=13 529) |
Partially adjusted* (N=13 529) |
Fully adjusted†
(N=11 913) | |
| OR (95% CI) | OR (95% CI) | OR (95% CI) | ||
| BNP group (pg/mL) | ||||
| <100 | 2018/3560 | 1.074 (0.987 to 1.168) | 1.055 (0.969 to 1.148) | 1.049 (0.956 to 1.150) |
| 100–399.9 (Reference) | 3127/5693 | 1.000 | 1.000 | 1.000 |
| 400+ | 2509/4276 | 1.165 (1.075 to 1.262) | 1.161 (1.072 to 1.258) | 1.192 (1.093 to 1.300) |
| BNP (per 100 pg/mL) | 7654/13 529 | 1.0034 (1.0010 to 1.0059) | 1.0035 (1.0010 to 1.0060) | 1.0037 (1.0010 to 1.0064) |
*Adjusted for age and sex.
†Adjusted for age, sex, ethnicity, IMD quintile, smoking status, systolic blood pressure, total cholesterol, body mass index, prior history of angina, myocardial infarction, ischaemic heart disease, diabetes, hypertension, stroke, atrial fibrillation, valve disease and calendar period (2004–2010, 2011–2018). n: number of hospital admissions at 1 year; N: number of persons with a new diagnosis of heart failure.