Table 2

Demographic and clinical data

BMT only
(n=40)
BMT+AC
(n=80)
Controls
(n=80)
P value
Age (years)50±1553±1350±130.115
Sex24M, 16F54M, 26F44M, 36F0.260
Body mass index (kg/m2)27.1±5.026.3±4.825.5±4.40.205
Height (cm)172±11172±8169±90.419
Weight (kg)76±1573±1774±160.113
Heart rate (bpm)70±1069±1067±110.120
BMT to TTE (years)6±66±60.399
Baseline LVEF by GHPS (%)63±561±70.023
Conditioning regime
 Myeloablative27%40%0.188
 Reduced intensity73%60%
ECOG status
 094%88%0.502
 16%12%
NYHA class
 1100%96%0.719
 20%4%
  • AC, anthracycline; BMT, bone marrow transplant; ECOG, Eastern Cooperative Oncology Group; GHPS, gated heart pool scan; LVEF, left ventricular ejection fraction; NYHA, New York Heart Association; TTE, transthoracic echocardiogram.