Associations between relative wall thickness and incident heart failure, overall and by sex
Total sample | Women | Men | ||||||||
HR | 95% CI | P value | Sex interaction P | HR | 95% CI | P value | HR | 95% CI | P value | |
Model 0 | 1.48 | 1.27 to 1.73 | <0.0001 | 0.151 | 1.17 | 0.83 to 1.65 | 0.39 | 1.55 | 1.28 to 1.86 | <0.0001 |
Model 1 | 1.23 | 1.04 to 1.46 | 0.02 | 0.101 | 0.91 | 0.62 to 1.33 | 0.62 | 1.35 | 1.12 to 1.64 | <0.01 |
Model 2 | 1.18 | 0.99 to 1.41 | 0.07 | 0.093 | 0.83 | 0.57 to 1.23 | 0.36 | 1.33 | 1.09 to 1.61 | <0.01 |
Model 3 | 1.14 | 0.95 to 1.36 | 0.16 | 0.075 | 0.81 | 0.55 to 1.19 | 0.28 | 1.30 | 1.06 to 1.58 | 0.01 |
Estimates are per 1-SD for relative wall thickness (SD=0.0634).
Model 0: Relative wall thickness alone.
Model 1: Relative wall thickness and sex stratified by age.
Model 2: Model 1+antihypertensive medication use.
Model 3: Model 2+body mass index, systolic blood pressure, diabetes, smoking and total/high-density lipoprotein cholesterol ratio.