Age-adjusted and sex-adjusted associations of high spectrum signal intensity coefficient with clinical risk factors and echocardiographic markers
Total sample | Women | Men | |||||||
Est. | SE | P value | Est. | SE | P value | Est. | SE | P value | |
Female sex* | −0.43 | 0.04 | <0.0001 | – | – | – | – | ||
Age (per SD)* | 0.16 | 0.02 | <0.0001 | 0.14 | 0.02 | <0.0001 | 0.18 | 0.03 | <0.0001 |
Body mass index (per SD) | 0.34 | 0.02 | <0.0001 | 0.31 | 0.02 | <0.0001 | 0.39 | 0.03 | <0.0001 |
Total/HDL cholesterol (per SD) | 0.15 | 0.02 | <0.0001 | 0.18 | 0.07 | <0.0001 | 0.13 | 0.03 | <0.0001 |
Systolic blood pressure (per SD) | 0.04 | 0.02 | 0.05 | 0.08 | 0.03 | <0.01 | −0.02 | 0.03 | 0.64 |
Antihypertensive treatment | 0.21 | 0.04 | <0.0001 | 0.25 | 0.05 | <0.0001 | 0.16 | 0.06 | 0.01 |
Diabetes | 0.40 | 0.06 | <0.0001 | 0.47 | 0.09 | <0.0001 | 0.35 | 0.09 | <0.0001 |
Smoking | 0.03 | 0.07 | 0.66 | 0.06 | 0.08 | 0.46 | −0.02 | 0.12 | 0.85 |
LVEF (per SD) | −0.01 | 0.003 | 0.01 | −0.01 | 0.004 | 0.02 | −0.01 | 0.005 | 0.16 |
E/e’ measurement (per SD) | 0.02 | 0.01 | 0.07 | 0.01 | 0.01 | 0.55 | 0.04 | 0.02 | 0.03 |
*Models including sex were adjusted for age only, and models including age were adjusted for sex only.
HDL, high-density lipoprotein; LVEF, left ventricular ejection fraction.