Associations of high spectrum signal intensity coefficient and relative wall thickness with incident heart failure, overall and by sex
| High spectrum SIC | Relative wall thickness* | |||||
| HR | 95% CI | P value | HR | 95% CI | P value | |
| Total sample | ||||||
| Model 0 | 1.44 | 1.19 to 1.74 | <0.001 | 1.42 | 1.21 to 1.67 | <0.0001 |
| Model 1 | 1.25 | 1.03 to 1.52 | 0.02 | 1.21 | 1.02 to 1.45 | 0.03 |
| Model 2 | 1.23 | 1.01 to 1.50 | 0.04 | 1.17 | 0.97 to 1.40 | 0.10 |
| Model 3 | 1.10 | 0.89 to 1.35 | 0.38 | 1.13 | 0.95 to 1.36 | 0.17 |
| Women | ||||||
| Model 0 | 1.76 | 1.31 to 2.37 | <0.001 | 1.06 | 0.73 to 1.53 | 0.76 |
| Model 1 | 1.61 | 1.20 to 2.17 | <0.01 | 0.83 | 0.56 to 1.23 | 0.35 |
| Model 2 | 1.54 | 1.13 to 2.10 | <0.01 | 0.78 | 0.53 to 1.17 | 0.23 |
| Model 3 | 1.47 | 1.06 to 2.03 | 0.02 | 0.77 | 0.51 to 1.16 | 0.21 |
| Men | ||||||
| Model 0 | 1.19 | 0.92 to 1.53 | 0.18 | 1.53 | 1.27 to 1.85 | <0.0001 |
| Model 1 | 1.10 | 0.86 to 1.42 | 0.45 | 1.35 | 1.12 to 1.64 | <0.01 |
| Model 2 | 1.09 | 0.83 to 1.41 | 0.51 | 1.32 | 1.09 to 1.61 | <0.01 |
| Model 3 | 0.95 | 0.72 to 1.25 | 0.71 | 1.29 | 1.06 to 1.58 | 0.01 |
Model 0: High spectrum signal intensity coefficient and relative wall thickness.
Model 1: High spectrum signal intensity coefficient, relative wall thickness, age and sex.
Model 2: Model 1+antihypertensive medication use.
Model 3: Model 2+body mass index, systolic blood pressure, diabetes, smoking, and total/high-density lipoprotein cholesterol ratio.
*Estimates are per 1-SD for high spectrum SIC and per 1-SD for relative wall thickness (SD=0.0634).
SIC, signal intensity coefficient.