Table 2

ECG characteristics of patients with amyloidosis fitted with ECGI (group 1) and the validation cohort (group 2)

ATTR-CA, group 1 (n=20)CA cohort, group 2 (n=30)
Heart rate, bpm (IQR)64 (56–77)73 (64–81)
Rhythm, n (%) Sinus rhythm10 (50)18 (60)
 Atrial fibrillation6 (30)9 (29)
 Atrial flutter2 (10)1 (3)
 Pacemaker2 (10)2 (8)
Low voltage*, n (%)4 (20)4 (12)
AV block, n (%)7 (35)10 (32)
PQ interval, ms (IQR)201 (190–228)196 (160–222)
Intraventricular conduction delay, n (%) LAFB6 (30)11 (38)
 LBBB2 (10)6 (20)
 RBBB4 (20)8 (26)
QRS interval, ms (IQR)100 (86–108)120 (95–156)
QTc interval, ms (IQR)451 (427–477)473 (445–503)
  • Values are given as median and IQR, or total number (n) and %.

  • *Low voltage was defined by an amplitude <0.5 mV in limb leads or <0.75 mV in precordial leads.

  • ATTR-CA, transthyretin cardiac amyloidosis; AV, atrioventricular block; bpm, beats per minute; CA, cardiac amyloidosis; ECGI, electrocardiographic imaging; LAFB, left anterior fascicular block; LBBB, left bundle branch block; RBBB, right bundle branch block.