Table 1

Baseline demographic and clinical characteristics of patients with amyloidosis and controls fitted with ECGI

ATTR-CA (n=20)Controls (n=11)P value
Age, years (IQR)76 (70–79)74 (64–78)0.528
Male gender, n (%)16 (80)4 (36)0.15
Body mass index, kg/m2 (IQR)25 (23–27)29 (25–32)0.079
NYHA functional class, n (%)0.391
II12 (60)6 (55)
III8 (40)4 (36)
Atrial fibrillation, n (%)11 (55)7 (64)0.641
Hypertension, n (%)5 (25)5 (47)0.244
Pacemaker or ICD, n (%)6 (30)2 (18)0.183
Therapy with beta-blockers, n (%)7 (35)9 (82)0.013
 NT-proBNP, pg/mL (IQR)3061 (1837–5136)948 (468–5586)0.113
 LVEF, % (IQR)51 (41–59)59 (51–60)0.165
 Interventricular septum, mm (IQR)22 (19–25)13 (12–17)0.001
  • Values are given as median and IQR, or total number (n) and %.

  • ATTR-CA, transthyretin cardiac amyloidosis ; ECGI, electrocardiographic imaging; ICD, intracardiac cardioverter defibrillator; LVEF, left ventricular ejection fraction; NT-proBNP, N-terminal prohormone of brain natriuretic peptide; NYHA, New York Heart Association.