Table 2

Association between baseline cardiometabolic comorbidities, cardiovascular/renal complications and all-cause death

	Primary outcomes		Secondary outcomes
	Any complication	All-cause death	Heart failure	Arrhythmia	Cardiac ischaemia	Cardiac arrest	Coagulation complications	Stroke	Renal injury
	OR (95% CI)		OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)	Or (95% CI)	Or (95% CI)
Any cardiometabolic comorbidity (ref: No)^*	1.93 (1.84 to 2.02)	1.21 (1.16 to 1.27)	4.19 (3.56 to 4.94)	1.69 (1.56 to 1.83)	2.61 (2.11 to 3.23)	1.24 (1.09 to 1.42)	1.49 (1.34 to 1.66)	1.19 (1.02 to 1.38)	2.08 (1.96 to 2.20)
Number of cardiometabolic comorbidities (ref: 0)^*
1	1.46 (1.39 to 1.54)	1.11 (1.05 to 1.17)	2.23 (1.86 to 2.67)	1.44 (1.31 to 1.57)	1.88 (1.48 to 2.39)	1.04 (0.89 to 1.22)	1.37 (1.21 to 1.54)	1.19 (1.00 to 1.41)	1.52 (1.42 to 1.62)
2	2.04 (1.93 to 2.15)	1.22 (1.16 to 1.29)	4.59 (3.85 to 5.46)	1.74 (1.58 to 1.91)	2.60 (2.05 to 3.30)	1.40 (1.19 to 1.63)	1.38 (1.21 to 1.58)	1.17 (0.98 to 1.41)	2.18 (2.04 to 2.33)
>2	3.10 (2.92 to 3.29)	1.42 (1.34 to 1.51)	8.01 (6.73 to 9.53)	2.23 (2.02 to 2.47)	4.24 (3.35 to 5.38)	1.46 (1.23 to 1.73)	2.03 (1.77 to 2.32)	1.21 (0.99 to 1.48)	3.41 (3.18 to 3.66)