Table 1

Baseline characteristics of patients implanted with CRT-D in French hospitals (2010–2019) with at least 1 year of follow-up, overall and according to vital status at 1 year

TotalAlive at 1 yearDead at 1 yearP value
(N=23 029)(n=21 425)(n=1604)
Age, years 67.7±9.967.4±9.970.9±9.4<0.0001
Sex (male) 18 156 (78.8)16 804 (78.4)1352 (84.3)<0.0001
Hypertension 13 449 (58.4)12 374 (57.8)1075 (67.0)<0.0001
Diabetes mellitus 7628 (33.1)6946 (32.4)682 (42.5)<0.0001
History of hospitalisation with congestion 18 761 (81.5)17 292 (80.7)1469 (91.6)<0.0001
History of pulmonary oedema 1572 (6.8)1335 (6.2)237 (14.8)<0.0001
Dilated cardiomyopathy 15 983 (69.4)14 915 (69.6)1068 (66.6)0.01
Coronary artery disease 13 720 (59.6)12 548 (58.6)1172 (73.1)<0.0001
Previous myocardial infarction 2155 (9.4)1935 (9.0)220 (13.7)<0.0001
Previous PCI 5912 (25.7)5353 (25.0)559 (34.9)<0.0001
Previous CABG 2683 (11.7)2385 (11.1)298 (18.6)<0.0001
Aortic stenosis 1079 (4.7)931 (4.3)148 (9.2)<0.0001
Aortic regurgitation 916 (4.0)804 (3.8)112 (7.0)<0.0001
Mitral regurgitation 3896 (16.9)3496 (16.3)400 (24.9)<0.0001
Atrial fibrillation 9214 (40.0)8272 (38.6)942 (58.7)<0.0001
Left BBB 8510 (37.0)7965 (37.2)545 (34.0)0.01
Right BBB 992 (4.3)880 (4.1)112 (7.0)<0.0001
Vascular disease 7567 (32.9)6808 (31.8)759 (47.3)<0.0001
Ischaemic stroke 777 (3.4)705 (3.3)72 (4.5)0.01
Intracranial bleeding 181 (0.8)155 (0.7)26 (1.6)0.0001
Smoker 3865 (16.8)3557 (16.6)308 (19.2)0.01
Dyslipidaemia 8701 (37.8)8008 (37.4)693 (43.2)<0.0001
Obesity 5129 (22.3)4745 (22.1)384 (23.9)0.1
Alcohol-related diagnoses 1782 (7.7)1624 (7.6)158 (9.9)0.001
Undernutrition 898 (3.9)752 (3.5)146 (9.1)<0.0001
Chronic kidney disease 2201 (9.6)1860 (8.7)341 (21.3)<0.0001
Lung disease 4117 (17.9)3700 (17.3)417 (26.0)<0.0001
Sleep apnoea syndrome 2377 (10.3)2184 (10.2)193 (12.0)0.02
Liver disease 1027 (4.5)877 (4.1)150 (9.4)<0.0001
Thyroid diseases 2125 (9.2)1899 (8.9)226 (14.1)<0.0001
Inflammatory disease 1317 (5.7)1163 (5.4)154 (9.6)<0.0001
Anaemia 2181 (9.5)1850 (8.6)331 (20.6)<0.0001
Previous cancer 1993 (8.7)1783 (8.3)210 (13.1)<0.0001
Cognitive impairment 219 (1.0)186 (0.9)33 (2.1)<0.0001
  • Values are n (%) or mean±SD.

  • BBB, bundle branch block; CABG, coronary artery bypass graft; CRT-D, cardiac resynchronisation therapy defibrillator; PCI, percutaneous coronary intervention.