Coronary artery disease at angiography and characteristics of the treated lesions
| All regions n=37 198 | Europe n=25 736 | Asia n=6614 | Africa/Middle East n=2438 | South America/Mexico n=2410 | |
| Extension of coronary disease | |||||
| Multivessel disease | 46.1% (17 147/37 198) | 45.4% (11 627/25 736) | 46.9% (3104/6614)* | 54.7% (1334/2438)* | 43.0% (1037/2410)* |
| 1-vessel disease | 53.8% (20 029/37 198) | 54.6% (14 062/25 736) | 53.1% (3509/6614)* | 45.2% (1101/2438)* | 56.3% (1357/2410) |
| 2-vessel disease | 29.2% (10 867/37 198) | 29.8% (7660/25 736) | 26.3% (1738/6614)* | 32.5% (792/2438)* | 28.1% (677/2410) |
| 3-vessel disease | 16.9% (6269/37 198) | 15.6% (4007/25 736) | 20.6% (1364/6614)* | 22.2% (541/2438)* | 14.8% (357/2410) |
| Vessel treated | |||||
| Left main | 3.1% (1158/37 198) | 3.2% (825/25 736) | 2.7% (179/6614)* | 2.6% (63/2438) | 3.8% (91/2410) |
| LAD | 51.6% (19 177/37 198) | 50.7% (13 048/25 736) | 51.7% (3420/6614) | 58.9% (1436/2438)* | 52.8% (1273/2410)* |
| CFX | 27.8% (10 343/37 198) | 28.0% (7195/25 736) | 25.1% (1660/6614)* | 33.7% (822/2438)* | 27.6% (666/2410) |
| RCA | 34.3% (12 765/37 198) | 34.5% (8878/25 736) | 33.5% (2214/6614) | 35.5% (865/2438) | 33.5% (808/2410) |
| Graft (arterial or venous) | 1.2% (444/37 198) | 1.4% (355/25 736) | 0.4% (29/6614)* | 1.4% (33/2438) | 1.1% (27/2410) |
| Lesion characteristics | |||||
| N of lesions identified, per patient | 1.8±1.1 (37 176) | 1.8±1.1 (25 734) | 1.9±1.2 (6613)* | 2.0±1.1 (2435)* | 1.8±1.0 (2394)* |
| N of lesions treated, per patient | 1.3±0.6 (37 158) | 1.3±0.6 (25 729) | 1.2±0.5 (6605)* | 1.5±0.7 (2432)* | 1.3±0.6 (2392) |
| Lesion characteristics, per patient | |||||
| CTO | 5.1% (1884/37 198) | 4.6% (1195/25 736) | 6.5% (428/6614)* | 4.5% (109/2438) | 6.3% (152/2410)* |
| Bifurcation | 11.8% (4395/37 198) | 13.1% (3361/25 736) | 7.8% (515/6614)* | 11.9% (290/2438) | 9.5% (229/2410)* |
| Small vessels | 43.7% (16 241/37 198) | 42.8% (11 016/25 736) | 43.2% (2858/6614) | 48.8% (1190/2438)* | 48.8% (1177/2410)* |
| Long lesions | 37.3% (13 885/37 198) | 34.8% (8960/25 736) | 41.9% (2768/6614)* | 45.9% (1120/2438)* | 43.0% (1037/2410)* |
| Lesion characteristics, per lesion | |||||
| ACC/AHA classification | |||||
| Type B2 lesion | 22.0% (10 923/49 751) | 22.2% (7721/34 797) | 20.4% (1642/8033)* | 16.5% (605/3659)* | 29.3% (955/3262) |
| Type C lesion | 20.6% (10 246/49 751) | 20.6% (7165/34 797) | 21.6% (1733/8033) | 17.0% (622/3659)* | 22.3% (726/3262) |
| Ostial lesions | 5.6% (2780/49 347) | 5.9% (2044/34 427) | 4.2% (337/8032)* | 6.4% (232/3642) | 5.1% (167/3246) |
| Moderate/severe calcification | 18.1% (8930/49 347) | 19.4% (6667/34 427) | 9.5% (762/8032)* | 15.1% (550/3642)* | 29.3% (951/3246) |
Data are mean±SD for continuous variables with or % (n) for categorical variables. The number of patients with available data is indicated in brackets. The p value for the comparison over all 4 regions was <0.0001 for all variables, except for left main (overall p=0.017) and RCA (overall p=0.21). A * indicates a p value <0.05 for the difference in characteristics between the region as compared with Europe.
Lesion characteristics at index procedure are reported. Small vessels are defined as at least 1 stent with diameter ≤2.75 mm. Long lesions are defined as at least 1 stent with length ≥25 mm.
ACC/AHA, American College of Cardiology/American Heart Association; CFX, circumflex; CTO, chronic total occlusion; LAD, left anterior descending artery; RCA, right coronary artery.