Table 3

Pressure–flow relationships

Healthy (33)AMI (52)MR (43)AS (40)P value
 ∆PAWP/∆CO (mm Hg/L/min)1.3±1.1*2.3±0.7*†1.9±1.4*3.0±1.3*†‡§<0.0001
 ∆mPAP/∆CO (mm Hg/L/min)2.0±1.5*2.8±1.3*3.0±1.6*†4.5±1.8*†‡§<0.0001
Rest→25 W
 ∆PAWP_25 W/∆CO_25 W (mm Hg/L/min)2.2±1.53.3±2.22.9±2.74.5±4.5†0.01
 ∆mPAP_25 W/∆CO_25 W (mm Hg/L/min)3.1±1.84.9±3.05.8±4.37.6±7.5†‡0.0009
  • Unadjusted analysis of variance was used to assess between-group differences, and Tukey’s honestly significant difference test was used to determine which group means differed for normally distributed data. Paired t-test was used to test between ∆peak and ∆25 W.

  • *P<0.05 vs ∆25 W.

  • †P<0.05 vs healthy.

  • ‡P<0.05 vs MR.

  • §P<0.05 vs AMI.

  • AMI, acute myocardial infarction; AS, aortic stenosis; CO, cardiac output; ∆CO, change in cardiac output; mPAP, mean pulmonary arterial pressure; MR, mitral regurgitation; ∆PAWP, change in pulmonary arterial wedge pressure; PAWP, pulmonary arterial wedge pressure.