Baseline characteristics of study participants
| CCTA arm (n=125) | SOC arm (n=125) | |
| Age mean (SD), years | 54.7 (13.3) | 56.0 (14.0) |
| Gender | Male: 93 (74%) | Male: 95 (77%) |
| Diabetes | 24 (19%) | 23 (18%) |
| Hypertension | 56 (45%) | 59 (47%) |
| Dyslipidaemia | 52 (42%) | 50 (40%) |
| Current or ex-smoker | 59 (47%) | 63 (50%) |
| Family history of ischaemic heart disease | 35 (28%) | 32 (25.6%) |
| Initial troponin concentration mean (SD), ng/L | 11.11 (8.56) | 11.52 (7.36) |
| Initial troponin concentration >99th percentile (14 ng/L) of a healthy reference population | 24 (19.2%) | 28 (22.4%) |
| Mean (SD) heart rate (beats/min) | 78 (14) | 78 (15) |
| Mean (SD) blood pressure (mm Hg) | – | – |
| Systolic | 141 (21) | 143 (22) |
| Diastolic | 85 (15) | 86 (14) |
| Medications | (n=124) | (n=123) |
| Antiplatelet therapy | 16 (13%) | 21 (17%) |
| Statin | 29 (23%) | 45 (36.6%) |
| ACE inhibitor | 29 (23%) | 24 (19.5%) |
| Angiotensin receptor blocker | 14 (11%) | 10 (8%) |
| Beta blocker | 13 (10%) | 20 (16%) |
| Calcium channel blocker | 30 (24%) | 30 (24%) |
| Diuretic agent | 11 (9%) | 16 (13%) |
| Oral diabetic agent | 21 (17%) | 22 (18%) |
| Insulin | 7 (5.6%) | 10 (8%) |
| Oral anticoagulant agent | 7 (5.6%) | 6 (5%) |
| Proton pump inhibitor | 22 (18%) | 25 (20%) |
CCTA, coronary CT angiography; SOC, standard of care.