Demographics for the total population and matched population
| Demographics | Unmatched patients | Propensity score-matched patients | ||||||
| PEARS (n=159) | VSRR (n=142) | SMD | P value | PEARS (n=80) | VSRR (n=80) | SMD | P value | |
| Age (years) | 31 (22–40) | 33 (26–41) | 0.24 | 0.06 | 31.7 (21.5–42.5) | 32 (26.25–38) | 0.08 | 0.63 |
| Male | 101 (63.5%) | 98 (69%) | 0.12 | 0.32 | 57 (71.3%) | 57 (71.3%) | 0.00 | 1.00 |
| Height (cm) | 186 (180–193) | 186 (180–194) | 0.05 | 0.91 | 188 (182–194) | 189 (182–194) | 0.09 | 0.97 |
| Aetiology | 0.21 | <0.01 | ||||||
| Marfan | 142 (89.3%) | 117 (82.4%) | 77 (96.3%) | 64 (80.0%) | ||||
| Loeys-Dietz | 15 (9.4%) | 23 (16.2%) | 2 (2.5%) | 15 (18.8%) | ||||
| ACTA2 mutation | 2 (1.3%) | 2 (1.4%) | 1 (1.3%) | 1 (1.3%) | ||||
| EuroSCORE II (%) | 1.0 (1.0–1.2) | 1.6 (1.0–2.1) | 0.43 | <0.001 | 1.0 (1.0–1.2) | 1.2 (1.0–1.6) | 0.09 | 0.35 |
| Previous cardiac surgery | 3 (1.9%) | 14 (9.9%) | 0.27 | <0.01 | 2 (2.5%) | 3 (3.8%) | 0.04 | 1.00 |
| Root diameter (mm) | 46 (43–48) | 49 (46–50) | 0.84 | <0.001 | 48 (46–50) | 48 (46–49) | −0.01 | 0.12 |
| Preoperative AR grade | 0.41 | <0.001 | −0.03 | 1.00 | ||||
| 0/4 | 123 (77.4%) | 81 (57%) | 55 (68.8%) | 56 (70.0%) | ||||
| 1/4 | 36 (22.6%) | 61 (43%) | 25 (31.3%) | 24 (30.0%) | ||||
| LVEF (%) | −0.06 | 0.65 | 0.00 | 1.00 | ||||
| Good >50% | 148 (93.1%) | 134 (94.4%) | 76 (95.0%) | 76 (95.0%) | ||||
| Moderate (31%–50%) | 11 (6.9%) | 8 (5.6%) | 4 (5.0%) | 4 (5.0%) | ||||
| Concomitant procedure planned | 21 (13.2%) | 26 (18.3%) | 0.13 | 0.22 | 12 (15.0%) | 13 (16.3%) | 0.03 | 1.00 |
Underlying aetiology was not used to match. Continuous variables were compared using Mann-Whitney U test, categorical variables via Χ2 or Fisher’s exact test. Matched data were compared using the Wilcoxon signed-rank test or the McNemar’s test for related samples.
SMD was used to evaluate balance between groups.
AR, aortic regurgitation; LVEF, left ventricular ejection fraction; PEARS, personalised external aortic root support; SMD, standardised mean difference; VSRR, valve-sparing root replacement.