Table 3

Subdistribution HRs for the within-group and between-group effect of birth weight on incident acute myocardial infarction (AMI)

OutcomesBirth weight <3.2 kg n=104 890
(1554 events)
Birth weight ≥3.2 kg n=149 280
(2083 events)
P value between group difference
Incident AMI, within-group effects0.85 (0.76 to 0.95) p=0.0051.01 (0.91 to 1.13) p=0.80p=0.02
Incident AMI, between-group effects1.15 (1.08 to 1.22)1.00p=6.0×10−5
  • Models adjusted for age, sex, social deprivation, maternal diabetes, maternal hypertension, maternal smoking and paternal diabetes. Results are subdistribution HRs per 1 kg increase in birth weight with corresponding 95% CIs. Significance level is set at p<0.025 for within-group and p<0.05 for between-group effects.