Table 3

One year event rates per 100 patient years in a contemporary multinational population with prevalent heart failure

BelgiumCanadaGermany*IsraelItalyNorwayPortugalSpainSwedenUKPooled event rates
(95% CI)
Tau
Cardiorenal diseasen/a4735 (21.9)10 974 (18.6)1243 (13.3)14 017 (23.5)7848 (11.8)128 (13.3)8846 (48.8)14 106 (8.8)8750 (13.1)19.3 (11.3 to 27.2)12.09
 Heart failure256 (19.7)2918 (13.5)9722 (16.6)770 (8.2)9987 (16.1)6343 (9.5)107 (11.1)6512 (37.2)12 271 (7.6)6869 (10.2)15.0 (9.5 to 20.4)8.75
 Chronic kidney disease251 (19.1)1817 (8.4)1280 (2.2)482 (5.2)1531 (2.3)1996 (2.9)38 (4.0)2334 (11.5)2425 (1.5)2644 (3.8)6.0 (2.7 to 9.4)5.40
Myocardial infarction113 (8.1)517 (2.4)652 (1.1)67 (0.7)1401 (2.1)1541 (2.3)21 (2.2)1060 (5.0)2289 (1.4)1320 (1.9)2.7 (1.4 to 3.9)2.06
Stroke45 (3.1)375 (1.7)579 (1.0)56 (0.6)1699 (2.6)282 (0.4)18 (1.9)765 (3.6)2784 (1.7)1368 (2.0)1.8 (1.2 to 2.4)1.02
Peripheral artery disease51 (3.5)284 (1.3)1619 (2.8)65 (0.7)846 (1.3)933 (1.4)1 (0.1)445 (2.1)1331 (0.8)451 (0.6)1.4 (0.8 to 2.0)0.98
All cause death172 (10.7)2649 (12.1)n/a1115 (11.9)n/a7920 (11.6)114 (11.9)2677 (13.1)21 966 (13.2)13 869 (19.9)13.1 (11.1 to 15.1)2.89
  • Values are number of events (event rate per 100 patient years).

  • Random effect estimates were used to calculate pooled values, and tau describes the estimated SD of the underlying data across countries. High heart failure event rates in Spain is partly explained by physicians being prone to admit a patient earlier instead of ambulatory outpatient clinic follow-up.

  • *Patients identified following a first hospitalisation for heart failure in a specified time period in Germany and Switzerland due to data availability, during 2019 and 2015–2019, respectively.

  • †Countries with inhospital mortality death only.

  • n/a, not available.