Baseline echocardiographic indices of matched and unmatched patients with moderate and asymptomatic severe AS, divided into heart valve clinic versus standard of care
Unmatched | Matched | ||||||
Total (N=2129) | Heart valve clinic (n=251) | Standard of care (n=1878) | P value | Heart valve clinic (n=156) | Standard of care (n=156) | P value | |
LVMi (g/m2) | 198±66 | 200.2±66.7 | 197.1±65.6 | 0.512 | 203±70 | 207±67 | 0.622 |
BP LVEF (%) | 55 (51–60) | 55 (55–61) | 55 (50–60) | <0.001 | 55 (55–60) | 57 (55–61) | 0.510 |
Severe AS | 919 (43.2) | 146 (58.2) | 773 (41.2) | <0.001 | 56 (35.9) | 52 (33.3) | 0.634 |
AVmax | 3.5 (3.2–4.1) | 3.7 (3.2–4.2) | 3.5 (3.2–4.1) | 0.009 | 3.7 (3.3–4.2) | 3.5 (3.2–4.2) | 0.153 |
AVA, cm2 | 1.01 (0.8–1.3) | 1 (0.8–1.2) | 1 (0.8–1.3) | 0.088 | 1 (0.8–1.3) | 1 (0.8–1.4) | 0.572 |
TR Pmax | 31±12 | 29±10 | 32±12 | 0.005 | 30±11 | 30±14 | 0.782 |
Moderate MR, n (%) | 102 (4.8) | 10 (4) | 92 (4.9) | 0.523 | 4 (2.6) | 7 (4.5) | 0.357 |
Continuous variables are presented as mean (SD) or median (LQ–UQ), when indicated; categorical ones are represented as n (%).
AS, aortic stenosis; AVA, aortic valve area; AVmax, aortic valve velocity maximum; BP LVEF, two-dimensional biplane left ventricular ejection fraction; LQ, lower quartile; LVMi, left ventricular mass indexed to BSA; MR, mitral regurgitation; TR Pmax, tricuspid regurgitation gradient; UQ, upper quartile.