Table 2

Baseline echocardiographic indices of matched and unmatched patients with moderate and asymptomatic severe AS, divided into heart valve clinic versus standard of care

UnmatchedMatched
Total
(N=2129)
Heart valve clinic
(n=251)
Standard of care
(n=1878)
P valueHeart valve clinic
(n=156)
Standard of care
(n=156)
P value
LVMi (g/m2)198±66200.2±66.7197.1±65.60.512203±70207±670.622
BP LVEF (%)55 (51–60)55 (55–61)55 (50–60)<0.00155 (55–60)57 (55–61)0.510
Severe AS919 (43.2)146 (58.2)773 (41.2)<0.00156 (35.9)52 (33.3)0.634
AVmax3.5 (3.2–4.1)3.7 (3.2–4.2)3.5 (3.2–4.1)0.0093.7 (3.3–4.2)3.5 (3.2–4.2)0.153
AVA, cm2 1.01 (0.8–1.3)1 (0.8–1.2)1 (0.8–1.3)0.0881 (0.8–1.3)1 (0.8–1.4)0.572
TR Pmax31±1229±1032±120.00530±1130±140.782
Moderate MR, n (%)102 (4.8)10 (4)92 (4.9)0.5234 (2.6)7 (4.5)0.357
  • Continuous variables are presented as mean (SD) or median (LQ–UQ), when indicated; categorical ones are represented as n (%).

  • AS, aortic stenosis; AVA, aortic valve area; AVmax, aortic valve velocity maximum; BP LVEF, two-dimensional biplane left ventricular ejection fraction; LQ, lower quartile; LVMi, left ventricular mass indexed to BSA; MR, mitral regurgitation; TR Pmax, tricuspid regurgitation gradient; UQ, upper quartile.