Table 4

Measures of discrimination performance for QRISK3 in the UK Biobank cohort in each age group, with 95% CIs

	Females				Males
Age group (years)	<45	45–55	55–65	65–75	35–45	45–55	55–65	>65
Harrell’s C-statistic (95% CI)	0.72 (0.69 to 0.75)	0.70 (0.69 to 0.71)	0.66 (0.65 to 0.67)	0.62 (0.61 to 0.63)	0.73 (0.70 to 0.75)	0.67 (0.66 to 0.68)	0.63 (0.63 to 0.64)	0.60 (0.59 to 0.61)
D-index (95% CI)	1.39 (1.20 to 1.58)	1.20 (1.12 to 1.28)	0.92 (0.87 to 0.97)	0.67 (0.61 to 0.73)	1.34 (1.20 to 1.48)	1.01 (0.95 to 1.07)	0.75 (0.71 to 0.79)	0.54 (0.49 to 0.60)