Table 3

Aortic dimensions and estimated aortic growth—RESVcue vs COMPARE trial group

Aortic levelRESVcue
(n=57)		COMPARE
(n=101)		P value adj*
Mean±SEMean±SE
Baseline (mm)
 Root†41.6±0.844.0±0.60.027
 Ascending†29.7±0.628.2±0.40.041
 Arch26.6±0.423.9±0.3<0.001
 Proximal descending26.7±0.623.8±0.4<0.001
 Distal descending22.0±0.3020.5±0.30.001
Follow-up (mm)
 Root†41.4±0.844.8±0.60.003
 Ascending†29.8±0.629.1±0.50.322
 Arch26.8±0.424.5±0.3<0.001
 Proximal descending26.6±0.624.4±0.40.001
 Distal descending22.0±0.320.8±0.30.009
Annual growth rate (mm/year)
 Root†−0.15±0.220.27±0.050.365
 Ascending†−0.06±0.220.28±0.050.365
 Arch0.06±0.150.19±0.040.470
 Proximal descending0.10±0.160.19±0.050.615
 Distal descending−0.04±0.130.10±0.040.470

  • Estimated aortic growth rates and differences in aortic growth rates were estimated using a linear mixed model, correcting for differences in follow-up duration, baseline aortic diameter, baseline body surface area and mean arterial pressure, with a random intercept on the subject level.

  • *P value after adjusted for multiple testing using the Benjamini-Hochberg procedure.

  • †For root and ascending diameter analysis, only patients with a native aorta were analysed (RESVcue, n=31, COMPARE group, n=70).