Table 1

Characteristics of the English prevaccination and postvaccination study cohorts. Variables used to match cases and controls within each cohort are highlighted in bold. ‘Partial’ vaccination status refers to patients who received one vaccination 14 days prior to their first SARS-CoV-2 infection. ‘Full’ vaccination status refers to patients who received two or more vaccinations 14 days prior to their first SARS-CoV-2 infection

Prevaccination casesPrevaccination controlsPostvaccination casesPostvaccination controls
Total number of patients780527 62057 550225 160
Mean age, years44.344.142.442.4
Sex (%)
 Male47.746.947.447.3
 Female52.353.152.652.7
Ethnicity (%)
 White90.891.493.894.5
 Asian7.47.12.62.2
 Black0.20.20.40.3
 Mixed0.00.00.10.1
 Other0.30.20.40.3
 Unknown1.31.12.82.6
Vaccination status (%)
 PartialN/AN/A8.07.6
 FullN/AN/A92.092.4
CHD severity (%)
 Mild66.5N/A68.5N/A
 Moderate29.1N/A27.4N/A
 Severe4.4N/A4.1N/A
 Pulmonary hypertension or cyanosis (%)2.1N/A1.6N/A
 Fontan circulation (%)0.1N/A0.1N/A
  • CHD, congenital heart disease.