Table 4

Correlations between V̇O_2peak and biochemistry/imaging parameters

		V̇O_2peak		Age-normalised/Sex- normalised V̇O_2peak
	N	Rho	P value	Rho	P value
FEV₁	41	0.468	0.002	0.491	0.001
Biochemistry
Creatinine	42	−0.118	0.458	−0.165	0.295
HS troponin-I	32	−0.478	0.006	−0.397	0.025
NT-proBNP	42	−0.662	<0.001	−0.626	<0.001
ACR	41	−0.305	0.053	−0.290	0.066
Cholesterol	42	−0.244	0.120	−0.243	0.122
Low-density lipoprotein	33	−0.228	0.201	−0.231	0.195
Haemoglobin	42	−0.147	0.352	−0.102	0.521
C reactive protein	36	−0.278	0.101	−0.377	0.023
White cell count	42	−0.308	0.047	−0.313	0.044
Neutrophil count	42	−0.427	0.005	−0.404	0.008
Lymphocyte count	42	0.371	0.015	0.347	0.024
Neutrophil-Lymphocyte ratio	42	−0.536	<0.001	−0.499	<0.001
Cardiac magnetic resonance imaging parameters
LV EDVi	37	0.338	0.041	0.222	0.187
LV ESVi	37	0.270	0.106	0.147	0.386
LV SVi	36	0.328	0.051	0.240	0.159
LV Mi	37	−0.340	0.039	−0.321	0.053
LV EF	37	−0.269	0.107	−0.181	0.285
RV EDVi	36	0.343	0.041	0.294	0.082
RV ESVi	36	0.108	0.529	0.089	0.607
RV SVi	35	0.433	0.009	0.456	0.006
RV EF	36	−0.074	0.667	−0.052	0.764
LA volume	36	−0.237	0.165	−0.183	0.285
Lowest T1	33	0.046	0.798	0.141	0.433
Transthoracic echocardiography parameters
TR velocity	19	−0.683	0.001	−0.649	0.003
LA EDV	37	−0.375	0.022	−0.438	0.007
LA ESV	37	−0.266	0.111	−0.313	0.059
LA GCS	37	0.252	0.132	0.288	0.084
LA GLS	37	0.280	0.093	0.342	0.038
LA EF	37	0.341	0.039	0.403	0.013
LA FAC	37	0.338	0.041	0.403	0.013

Correlations between each parameter and both the observed and age-normalised/sex-normalised V̇O_2peak are quantified using Spearman’s rank correlation coefficients (rho). Bold p values are significant at p<0.05.
ACR, urine albumin to creatinine ratio; EDVi, end-diastolic volume (indexed); EF, ejection fraction; ESVi, end-systolic volume (indexed); FAC, fractional area change; FEV₁, forced expiratory volume in 1 s; GCS, global circumferential strain; GLS, global longitudinal strain; HS, high sensitivity; LA, left atrial; LV, left ventricular; Mi, mass indexed; NT-proBNP, N-terminal pro B-type natriuretic peptide; RV, right ventricular; SVi, stroke volume indexed; TR, tricuspid regurgitation; V̇O_2peak, peak oxygen uptake.