Physiology measurement | All participants (n=151) | Microvascular angina (MVA) (n=78) | Vasospastic angina (VSA) (n=25) | Mixed MVA and VSA (n=31) | Non-cardiac symptoms (n=17) | Kruskal-Wallis p value |
FFR | 0.88 (0.83–0.92) | 0.89 (0.84–0.93) | 0.85 (0.82–0.89) | 0.86 (0.82–0.92) | 0.88 (0.84–0.92) | 0.207 |
MeanTmn Rest | 0.78 (0.50–1.07) | 0.82 (0.49–1.10) | 0.67 (0.51–1.07) | 0.78 (0.55–1.29) | 0.75 (0.34–0.93) | 0.852 |
MeanTmn Hyp | 0.27 (0.20–0.39) | 0.28 (0.21–0.42) | 0.22 (0.17–0.27) | 0.37 (0.29–0.50) | 0.22 (0.15–0.29) | <0.001 |
CFR | 2.6 (1.9–3.6) | 2.3 (1.8–3.5) | 3.2 (2.7–4.0) | 2.0 (1.6–2.9) | 3.2 (2.3–4.6) | <0.001 |
IMR | 19 (14–29) | 23 (15–32) | 16 (13–20) | 28 (18–37) | 16 (11–20) | <0.001 |
MRR | 3.3 (2.4–4.4) | 3.1 (2.1–4.2) | 4.0 (3.2–5.0) | 2.7 (2.2–3.5) | 4.3 (3.0–5.6) | <0.001 |
RRR | 3.1 (2.3–4.1) | 2.8 (2.1–4.0) | 3.7 (3.2–5.0) | 2.6 (2.1–3.3) | 3.8 (2.8–4.7) | 0.002 |
All values are reported as median (IQR).
CFR, coronary flow reserve; FFR, fractional flow reserve; IMR, Index of Microcirculatory Resistance; MeanTmn Hyp, mean transit time at hyperaemia; MeanTmn Rest, mean transit time at rest; MRR, microvascular resistance reserve; RRR, resistive reserve ratio.