Table 2

Costs of diagnosis and treatment for each strategy

Grand costsCholesterolDNADNA+CholM-ve DFHDNA+CholM-ve DFH+PFH
Total cost of diagnosis£839£1240£1280£1519
Total cost of treatment£43 737£49 677£51 390£53 280
Combined total cost£44 576£50 918£52 670£54 799
  • CholM-ve, cascade testing using LDL-C in relatives of mutation-negative index cases; DFH, definite familial hypercholesterolaemia; PFH, possible familial hypercholesterolaemia.