Table 2

Serum concentrations of type III procollagen peptide (P III P), 7S domain of type IV collagen (7S collagen), and cardiac troponin T (TnT)

Patient NoCK (IU/ml)P III P (U/ml)7S collagen (ng/ml)TnT (ng/ml)LVEDP (mm Hg)CI (l/min/m2)LVEDVI (ml/m2)EF (%)
11430.54.6< 0.10113.628540
2420.74.2< 0.10142.219317
31560.62.8< 0.10233.3214953
431 1.6 2.9 0.15 181.848347
5520.63.3< 0.10102.478024
6390.6 5.7 0.22 162.0711324
71240.83.9< 0.10206.4310569
876 1.0 5.1 0.27 122.709645
9730.73.9< 0.10163.3912451
101230.6 6.5 0.26 172.6711358
1151 1.1 3.8< 0.10152.0112239
12990.8 9.1 < 0.10121.9310551
13400.84.5< 0.1092.9110049
141250.6 8.2 < 0.10482.787636
15840.8 7.1 0.39 311.8514526
16106 1.8 3.4< 0.10255.4719040
17680.4 6.4 < 0.10263.281879
18320.64.9< 0.10233.6212945
191190.44.7< 0.1093.3810452
20760.6 6.8 < 0.1092.0810626
21860.64.3< 0.10122.9111330
  • Eleven of the 21 patients had significantly raised serum concentrations (shown in bold) of P III P, 7S collagen, or TnT, even though their CK values were within the normal range.

  • CK, creatine kinase; LDEDP, left ventricular end diastolic pressure; CI, cardiac index; LDEDVI, left ventricular end diastolic volume index; EF, left ventricular ejection fraction.