Table 1

Clinical characteristics of the patients studied and findings on 24 hour ambulatory ECG

Age/sexCardiac diagnosisNicorandil (mg/day)1-150 ControlPVC/24 h1-151
at 4 weeks
169/FAP30–6010728 (2)31210 (2)191Positive
265/FDCM30–6030504 (4b)54456 (4b)79Positive
350/M(−)30–602884822584 (2)−22Positive
473/MHT30–4515960 (4b)6384 (4b)−60Positive
591/MOMI30–303432 (4b)6240 (4b)82Positive
681/FAR,MR30–3013343 (4b)25152 (4b)88Positive
772/M(−)15–152160 (2)2927 (2)36Positive
867/MHT30–302920 (3)7056 (4b)142Positive
988/FHT30−3054024 (4b)35376 (4b)−35Positive
1054/F(−)30–457874 (2)8400 (2)7Bidirectional
1145/F(−)30–456288 (2)19608 (2)212Bidirectional
1257/M(−)30–301872 (2)2928 (2)56Bidirectional
1362/MHT30–455952 (2)6816 (2)15Bidirectional
1419/M(−)30–308160 (2)7728 (2)−5Bidirectional
1584/F(−)15–151488 (4a)840 (4a)−44Bidirectional
1666/FHT30–4511736 (3)2520 (2)−79Bidirectional
1746/FSSS15–1519265 (3)2357 (3)−88Bidirectional
1843/F(−)30–3013104 (2)1416 (2)−89Bidirectional
1961/MSSS30–302877 (4b)93 (4b)−97Bidirectional
2065/F(−)30–453048 (2)0−100Bidirectional
  • 1-150 Daily doses of nicorandil during the first 2 weeks and the next 2 weeks.

  • 1-151 Frequency of premature ventricular contractions (PVC) per 24 hours;4 weeks after nicorandil treatment.

  • 1-153 Correlation between the frequency of PVC and heart rate before treatment. Lown’s classification of PVC10 is given parentheses.

  • AP, angina pectoris; AR, MR, aortic and mitral regurgitation; DCM, dilated cardiomyopathy; HT, hypertension; OMI, old myocardial infarction; SSS, sick sinus syndrome.