Table 2

Clinical outcome of the early (before 1991) and late (after 1991) transplant patients

Early (n=147)Late (n=114)
Follow up (months)
 Median9641
 Range69–14612–69
Acute rejection
 Mean number of episodes (SD)1.4 (1.3)2.4 (1.7)*
 Patients with 0 episodes3814
 Patients with > 2 episodes2567
 Mean courses of treatment (SD)1.5 (1.5)3.2 (2.3)
Mean number of infections within first year1.4 (1.3)1.8 (1.6)
Overall mean number of infections (SD)3.5 (2.8)2.9 (2.4)
Number with CMV disease2418
Number with non-skin malignancy
 0–41 months6/1478/57§
 > 41 months12 0 
Number with skin malignancy
 0– 41 months30 
 > 41 months60
Graft vascular disease
 < 12 months5/1472/106
 < 41 months21/1476/57
Mean LVEF at 1 year (SD)65 (11)%65 (11)%
  • Fifty seven patients had follow up of at least 41 months.

  • 95% confidence intervals: * −1.4 to −0.6; −2.2 to −1.3; −0.8 to −0.1; * § −0.2 to −0.004.

  • LVEF, left ventricular ejection fraction.