Twelve minute walk data on epoprostenol (PGI2)
| Patient | Diagnosis | Distance (m) | Rest (s) | ΔSaO2(%) | ΔHR (%) | Duration (weeks) | Dose PGI2 (ng/kg/min) |
|---|---|---|---|---|---|---|---|
| 1 | TEPH | 360 | 0 | — | — | 19 | 5.5 |
| 2 | PPH | 620 | 0 | 11.1 | 41.3 | 7 | 20 |
| 3 | PPH | 680 | 0 | — | — | 4.5 | 6.3 |
| 4 | TEPH | 520 | 0 | 4.1 | 28.6 | 5 | 15.8 |
| 5 | PPH | 490 | 125 | — | — | 4 | 4 |
| 6 | TEPH | 700 | 0 | 4.3 | 42.5 | 4 | 3.8 |
| 7 | PPH | 760 | 0 | 3.1 | 26.8 | 5 | 6.9 |
| 8 | PPH | 600 | 0 | — | 35.8 | 7.5 | 7.3 |
| Mean | 591** | 164-150 | 6 | 35 | 7 | 8.7 | |
| (SEM) | (46) | (16) | (1.8) | (3.2) | (1.8) | (2.2) |
↵4-150 p < 0.05, **p < 0.01 compared to baseline.
ΔHR (%), percentage increase in heart rate; ΔSaO2(%), percentage drop in oxygen saturation; PPH, primary pulmonary hypertension; TEPH, thromboembolic pulmonary hypertension.