Relative odds of incident ischaemic heart disease by fifths of insulin distribution in non-diabetic men in the Caerphilly cohort (n = 1896)
| Insulin range (mU/l) | Men (n) | Events (n) | Relative odds | ||||
|---|---|---|---|---|---|---|---|
| Age adjusted only (95%CI) | Multivariate3-150 | ||||||
| ⩽ 3.0 | 403 | 32 | 1.00 | 1.00 | |||
| 3.1–4.6 | 368 | 39 | 1.45 (0.88, 2.37) | 1.34 (0.81, 2.23) | |||
| 4.7–6.5 | 369 | 45 | 1.68 (1.04, 2.71) | 1.49 (0.90, 2.45) | |||
| 6.6–10.0 | 390 | 53 | 1.95 (1.22, 3.11) | 1.47 (0.90, 2.42) | |||
| 10.1– | 366 | 52 | 2.05 (1.28, 3.27) | 1.27 (0.75, 2.17) | |||
| Total | 1896 | 221 | |||||
| Heterogeneity test | χ2 = 11.9, | χ2 = 3.29, | |||||
| 4 df, p = 0.01 | 4 df, p = 0.51 | ||||||
| Trend test | χ2 = 10.8, | χ2 = 0.79, | |||||
| 1 df, p = 0.001 | 1 df, p = 0.37 | ||||||
↵3-150 Included in multivariate model are: age, pre-existing IHD, smoking habit, diastolic blood pressure, total and HDL cholesterol, log triglyceride, and glucose.