No medication | ACE inhibitor | Diuretic | ACE inhibitor+ diuretic | |
---|---|---|---|---|
Sex (male/female) | ||||
Without β blocker | 264/293 | 12/9 | 3/7 | 12/20 |
With β blocker | 30/42 | 2/5 | 9/13 | 5/2 |
Age (years) | ||||
Without β blocker | 57.0 (0.2) | 60.8 (1.9) | 59.7 (2.5) | 61.7 (1.3) |
With β blocker | 58.7 (0.7)1-150 | 55.7 (2.4)1-150 | 60.3 (1.4) | 63.5 (2.6) |
Indication for treatment (HTN/CAD) | ||||
Without β blocker | 18/0 | 10/2 | 30/4 | |
With β blocker | 62/15 | 7/0 | 20/2 | 7/0 |
Systolic blood pressure (mm Hg) | ||||
Without β blocker | 146 (1) | 157 (5)† | 151 (8) | 154 (3.7)† |
With β blocker | 147 (2) | 154 (5) | 153 (5) | 148 (7) |
Heart rate (beats/min) | ||||
Without β blocker | 71 (0.5) | 69 (2.4) | 80 (3) | 74 (2) |
With β blocker | 67 (2)1-150 | 67 (4) | 66 (2)1-150 | 70 (3) |
Fractional shortening (%) | ||||
Without β blocker | 36.3 (0.3) | 34.5 (1.9) | 33.0 (3.3) | 35.7 (1.8) |
With β blocker | 36.5 (0.9) | 33.7 (3.1) | 38.6 (2.3) | 36.3 (2.6) |
Absolute numbers are given for men and women, and indication for treatment. Means (SEM) are given for other demographic and haemodynamic parameters.
↵1-150 p < 0.05 v respective treatment group without β blocker; †p < 0.05 v no medication.
HTN, arterial hypertension; CAD, coronary artery disease.