Table 3

Sex differences in heart rate variability measures (ln transformed) in supine position

MeasuresControlled for age Controlled for age and heart rate
Men mean (SD)Women mean (SD)pMen mean (SD)Women mean (SD)p
Free breathing
SD3.71 (0.49)3.57 (0.34)0.0073.70 (0.40)3.65 (0.29)0.191
RMSSD3.26 (0.49)3.26 (0.42)0.9163.25 (0.36)3.38 (0.34)0.003
Area very low5.80 (0.98)5.44 (0.72)0.0015.78 (0.83)5.59 (0.65)0.029
Area low5.40 (1.13)5.02 (0.78)0.0015.40 (0.96)5.14 (0.73)0.010
Area high4.84 (1.12)4.85 (0.93)0.9204.83 (0.86)5.09 (0.77)0.008
Total PS6.61 (0.98)6.33 (0.68)0.0056.61 (0.78)6.49 (0.58)0.156
Ratio (low to high)5.19 (0.77)4.78 (0.79)< 0.0015.18 (0.76)4.65 (0.74)< 0.001
Metronomic breathing
SD3.60 (0.44)3.55 (0.34)0.2903.59 (0.38)3.61 (0.31)0.631
RMSSD3.22 (0.47)3.26 (0.45)0.4773.20 (0.37)3.36 (0.37)< 0.001
Area very low5.47 (0.96)5.29 (0.73)0.0405.48 (0.86)5.37 (0.71)0.243
Area low4.98 (1.00)4.66 (0.80)0.0034.96 (0.91)4.76 (0.77)0.047
Area high4.77 (1.09)4.97 (1.01)0.1034.74 (0.90)5.20 (0.87)< 0.001
Total PS6.35 (0.88)6.24 (0.69)0.2406.32 (0.74)6.37 (0.62)0.546
Ratio (low to high)4.81 (0.80)4.30 (0.90)< 0.0014.82 (0.78)4.18 (0.84)< 0.001
  • SD, standard deviation of RR interval; RMSSD, root mean square of differences of successive RRs; area very low, the area at very low frequency (0.0033 to < 0.04 Hz); area low, the area at low frequency (0.04 to < 0.15 Hz); area high, the area at high frequency (0.15 to < 0.40 Hz); total PS, total power spectrum (0.0033 to < 0.40 Hz); ratio low to high, ratio of low frequency to high frequency.

  • The values for the SD and RMSSD are in ms and the values for the areas and total power are in ms2.

  • p values from t test for differences in means.